| Standard name |
ZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_DN |
| Systematic name |
MM459 |
| Brief description |
The authors compared the cellular composition and gene expression profiles of responsive and nonresponsive tumors from BALB/cArc, BALB/cJAusb, and C57BL6/J mice before immune checkpoint blockade (ICB) and validated the findings in cohorts of patients with cancer treated with ICB antibodies. |
| Full description or abstract |
Experiments were performed using Renca renal cell carcinoma cell lines. |
| Collection |
M2: Curated
CGP: Chemical and Genetic Perturbations |
| Source publication |
Pubmed 31316010 Authors: Zemek RM,De Jong E,Chin WL,Schuster IS,Fear VS,Casey TH,Forbes C,Dart SJ,Leslie C,Zaitouny A,Small M,Boon L,Forrest ARR,Muiri DO,Degli-Esposti MA,Millward MJ,Nowak AK,Lassmann T,Bosco A,Lake RA,Lesterhuis WJ |
| Exact source |
Data file S1. Renca |
| Related gene sets |
(show 2 additional gene sets from the source publication)
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| External links |
https://www.ncbi.nlm.nih.gov/pubmed/31316010
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| Filtered by similarity ?
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| Source species |
Mus musculus |
| Contributed by |
Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX)) |
Source platform or
identifier namespace |
MOUSE_GENE_SYMBOL |
| Dataset references |
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| Download gene set |
format: grp | gmt | xml | json | TSV metadata |
| Compute overlaps ? |
(show collections to investigate for overlap with this gene set)
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| Compendia expression profiles ? |
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| Advanced query |
Further investigate
these 8 genes
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| Show members |
(show 8 source identifiers mapped to 8 genes)
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| Version history |
2022.1.Mm: First Introduced.
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