Mouse Gene Set: REACTOME_CASPASE_ACTIVATION_VIA_EXTRINSIC_APOPTOTIC_SIGNALLING_PATHWAY
For the Human gene set with the same name, see REACTOME_CASPASE_ACTIVATION_VIA_EXTRINSIC_APOPTOTIC_SIGNALLING_PATHWAY
Standard name
REACTOME_CASPASE_ACTIVATION_VIA_EXTRINSIC_APOPTOTIC_SIGNALLING_PATHWAY
Systematic name
MM15176
Brief description
Caspase activation via extrinsic apoptotic signalling pathway
Full description or abstract
Collection
M2: Curated CP: Canonical Pathways CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-MMU-5357769
Related gene sets
External links
https://www.reactome.org/content/detail/R-MMU-5357769
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Reactome
Source platform or identifier namespace
Mouse_Ensembl_Gene_ID
Dataset references
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Further investigate
these 19 genes
Show members
(show 19 source identifiers mapped to 19 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
ENSMUSG000000008 17
14103
Fasl
Fas ligand [Source:MGI Symbol;A...
ENSMUSG000000214 08
19766
Ripk1
receptor (TNFRSF)-interacting s...
ENSMUSG000000220 74
21933
Tnfrsf10b
tumor necrosis factor receptor ...
ENSMUSG000000247 78
14102
Fas
Fas cell surface death receptor...
ENSMUSG000000257 79
17087
Ly96
lymphocyte antigen 96 [Source:M...
ENSMUSG000000260 29
12370
Casp8
caspase 8 [Source:MGI Symbol;Ac...
ENSMUSG000000260 31
12633
Cflar
CASP8 and FADD-like apoptosis r...
ENSMUSG000000269 42
22030
Traf2
TNF receptor-associated factor ...
ENSMUSG000000289 14
12371
Casp9
caspase 9 [Source:MGI Symbol;Ac...
ENSMUSG000000310 77
14082
Fadd
Fas associated via death domain...
ENSMUSG000000316 28
12367
Casp3
caspase 3 [Source:MGI Symbol;Ac...
ENSMUSG000000318 87
71609
Tradd
TNFRSF1A-associated via death d...
ENSMUSG000000390 05
21898
Tlr4
toll-like receptor 4 [Source:MG...
ENSMUSG000000393 04
22035
Tnfsf10
tumor necrosis factor (ligand) ...
ENSMUSG000000407 60
72993
Appl1
adaptor protein, phosphotyrosin...
ENSMUSG000000471 23
106759
Ticam1
TIR domain containing adaptor m...
ENSMUSG000000514 39
12475
Cd14
CD14 antigen [Source:MGI Symbol...
ENSMUSG000000561 30
225471
Ticam2
TIR domain containing adaptor m...
ENSMUSG000000605 34
13176
Dcc
DCC netrin 1 receptor [Source:M...
Version history
2026.1.Mm: Updated to Reactome 95
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The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .