Mouse Gene Set: RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP
For the Human gene set with the same name, see RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP
Standard name
RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP
Systematic name
MM694
Brief description
Genes up-regulated in the brain cortex of mice that were exposed to an enriched learning environment for 2 or 14 days.
Full description or abstract
An enriched environment is known to promote structural changes in the brain and to enhance learning and memory performance in rodents [Hebb, D. O. (1947) Am. Psychol. 2, 306-307]. To better understand the molecular mechanisms underlying these experience-dependent cognitive changes, we have used high-density oligonucleotide microarrays to analyze gene expression in the brain. Expression of a large number of genes changes in response to enrichment training, many of which can be linked to neuronal structure, synaptic plasticity, and transmission. A number of these genes may play important roles in modulating learning and memory capacity.
Collection
M2: Curated CGP: Chemical and Genetic Perturbations
Source publication
Pubmed 11070096 Authors: Rampon C,Jiang CH,Dong H,Tang YP,Lockhart DJ,Schultz PG,Tsien JZ,Hu Y
Exact source
Table 1: 3h and 6 hr > 0
Related gene sets
(show 2 additional gene sets from the source publication)
(show 11 gene sets from the same authors)
External links
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Source species
Mus musculus
Contributed by
John Newman (University of Washington)
Source platform or identifier namespace
AFFY_Mu11K
Dataset references
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Further investigate
these 21 genes
Show members
(show 24 source identifiers mapped to 21 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
AA118268
101437
Dhx32
DEAH-box helicase 32 (putative) [...
AA407689_rc_s_at
26446
Psmb3
proteasome (prosome, macropain) s...
AA512103_i_at
AF027963_s_at
22433
Xbp1
X-box binding protein 1 [Source:M...
D32167_s_at
22771
Zic1
zinc finger protein of the cerebe...
D50621_s_at
13385
Dlg4
discs large MAGUK scaffold protei...
ET63385_at
M19380_f_at
12315
Calm3
calmodulin 3 [Source:MGI Symbol;A...
M72414_s_at
17758
Map4
microtubule-associated protein 4 ...
Msa.16315.0_f_at
U03184_s_at
13043
Cttn
cortactin [Source:MGI Symbol;Acc:...
U05333_f_at
21371
Tbca
tubulin cofactor A [Source:MGI Sy...
X73985_s_at
12308
Calb2
calbindin 2 [Source:MGI Symbol;Ac...
aa030563_f_at
218490
Btf3
basic transcription factor 3 [Sou...
aa110732_s_at
59288
Dctn5
dynactin 5 [Source:MGI Symbol;Acc...
aa174982_s_at
12721
Coro1a
coronin, actin binding protein 1A...
aa259803_s_at
13437
Dnpep
aspartyl aminopeptidase [Source:M...
aa274721_s_at
53895
Clpp
caseinolytic mitochondrial matrix...
c75968_rc_s_at
30941
Usp21
ubiquitin specific peptidase 21 [...
c79022_rc_s_at
170750
Xpnpep1
X-prolyl aminopeptidase (aminopep...
d29763_s_at
20370
Sez6
seizure related gene 6 [Source:MG...
d83999_s_at
20021
Polr2c
polymerase (RNA) II (DNA directed...
m31131_s_at
12558
Cdh2
cadherin 2 [Source:MGI Symbol;Acc...
u06670_s_at
22359
Vldlr
very low density lipoprotein rece...
Version history
2022.1.Mm: First Introduced.
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