Mouse Gene Set: GOMF_DEATH_DOMAIN_BINDING
For the Human gene set with the same name, see GOMF_DEATH_DOMAIN_BINDING
Standard name
GOMF_DEATH_DOMAIN_BINDING
Systematic name
MM14251
Brief description
Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. [GOC:BHF, GOC:rl, InterPro:IPR000488, Pfam:PF00531]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:MF: GO Molecular Function
Source publication
Exact source
GO:0070513
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0070513
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
Download gene set
format: grp | gmt | xml | json | TSV metadata
Compute overlaps ?
(show collections to investigate for overlap with this gene set)
Compendia expression profiles ?
NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds )
Mouse Transcriptomic BodyMap compendium
Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query
Further investigate
these 13 genes
Show members
(show 13 source identifiers mapped to 13 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
12028
12028
Bax
BCL2-associated X protein [Source:MGI Symbol...
12043
12043
Bcl2
B cell leukemia/lymphoma 2 [Source:MGI Symbo...
12048
12048
Bcl2l1
BCL2-like 1 [Source:MGI Symbol;Acc:MGI:88139]
12905
12905
Cradd
CASP2 and RIPK1 domain containing adaptor wi...
14694
14694
Rack1
receptor for activated C kinase 1 [Source:MG...
15944
15944
Irgm1
immunity-related GTPase family M member 1 [S...
16145
16145
Igtp
interferon gamma induced GTPase [Source:MGI ...
17210
17210
Mcl1
myeloid cell leukemia sequence 1 [Source:MGI...
19766
19766
Ripk1
receptor (TNFRSF)-interacting serine-threoni...
223453
223453
Dap
death-associated protein [Source:MGI Symbol;...
54396
54396
Irgm2
immunity-related GTPase family M member 2 [S...
71609
71609
Tradd
TNFRSF1A-associated via death domain [Source...
76747
76747
Dapl1
death associated protein-like 1 [Source:MGI ...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
See MSigDB license terms here . Please note that certain gene sets
have special access terms.