Mouse Gene Set: GOCC_VCP_NPL4_UFD1_AAA_ATPASE_COMPLEX
For the Human gene set with the same name, see GOCC_VCP_NPL4_UFD1_AAA_ATPASE_COMPLEX
Standard name
GOCC_VCP_NPL4_UFD1_AAA_ATPASE_COMPLEX
Systematic name
MM12213
Brief description
A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry). [PMID:11813000, PMID:16179952]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0034098
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0034098
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Further investigate
these 8 genes
Show members
(show 8 source identifiers mapped to 8 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
14084
14084
Faf1
Fas-associated factor 1 [Source:MGI Symbol;A...
217365
217365
Nploc4
NPL4 homolog, ubiquitin recognition factor [...
22230
22230
Ufd1
ubiquitin recognition factor in ER-associate...
224111
224111
Ubxn7
UBX domain protein 7 [Source:MGI Symbol;Acc:...
225896
225896
Ubxn1
UBX domain protein 1 [Source:MGI Symbol;Acc:...
269523
269523
Vcp
valosin containing protein [Source:MGI Symbo...
67664
67664
Rnf125
ring finger protein 125 [Source:MGI Symbol;A...
76577
76577
Faf2
Fas associated factor family member 2 [Sourc...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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