Mouse Gene Set: GOCC_TORC2_COMPLEX
For the Human gene set with the same name, see GOCC_TORC2_COMPLEX
Standard name
GOCC_TORC2_COMPLEX
Systematic name
MM12146
Brief description
A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p. [GOC:bf, GOC:jh, PMID:14736892, PMID:15780592, PMID:16469695, PMID:21548787]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0031932
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0031932
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Further investigate
these 9 genes
Show members
(show 9 source identifiers mapped to 9 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
109270
109270
Prr5
proline rich 5 (renal) [Source:MGI Symbol;A...
227743
227743
Mapkap1
mitogen-activated protein kinase associated...
230784
230784
Sesn2
sestrin 2 [Source:MGI Symbol;Acc:MGI:2651874]
56716
56716
Mlst8
MTOR associated protein, LST8 homolog (S. c...
56717
56717
Mtor
mechanistic target of rapamycin kinase [Sou...
72446
72446
Prr5l
proline rich 5 like [Source:MGI Symbol;Acc:...
75425
75425
Tti1
TELO2 interacting protein 1 [Source:MGI Sym...
75747
75747
Sesn3
sestrin 3 [Source:MGI Symbol;Acc:MGI:1922997]
78757
78757
Rictor
RPTOR independent companion of MTOR, comple...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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