Mouse Gene Set: GOCC_PYRUVATE_DEHYDROGENASE_COMPLEX
For the Human gene set with the same name, see GOCC_PYRUVATE_DEHYDROGENASE_COMPLEX
Standard name
GOCC_PYRUVATE_DEHYDROGENASE_COMPLEX
Systematic name
MM17433
Brief description
A multi-enzyme complex that catalyzes the oxidative decarboxylation of pyruvate to form acetyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: pyruvate dehydrogenase (E1, which may be a homodimer or a heterotetramer of two alpha and two beta subunits, depending on species), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present. [PMID:36863425]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0045254
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0045254
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 8 genes
Show members
(show 8 source identifiers mapped to 8 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
13382
13382
Dld
dihydrolipoamide dehydrogenase [Source:MGI Sy...
18597
18597
Pdha1
pyruvate dehydrogenase E1 alpha 1 [Source:MGI...
18598
18598
Pdha2
pyruvate dehydrogenase E1 alpha 2 [Source:MGI...
18604
18604
Pdk2
pyruvate dehydrogenase kinase, isoenzyme 2 [S...
228026
228026
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1 [S...
235339
235339
Dlat
dihydrolipoamide S-acetyltransferase [Source:...
27402
27402
Pdhx
pyruvate dehydrogenase complex, component X [...
68263
68263
Pdhb
pyruvate dehydrogenase (lipoamide) beta [Sour...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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