Mouse Gene Set: GOCC_NUCLEAR_EXOSOME_RNASE_COMPLEX
For the Human gene set with the same name, see GOCC_NUCLEAR_EXOSOME_RNASE_COMPLEX
Standard name
GOCC_NUCLEAR_EXOSOME_RNASE_COMPLEX
Systematic name
MM11701
Brief description
A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. [PMID:17174896, PMID:20531386, PMID:26726035]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0000176
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0000176
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 15 genes
Show members
(show 15 source identifiers mapped to 15 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
107071
107071
Wdr74
WD repeat domain 74 [Source:MGI Symbol;Acc...
109075
109075
Exosc4
exosome component 4 [Source:MGI Symbol;Acc...
227715
227715
Exosc2
exosome component 2 [Source:MGI Symbol;Acc...
27998
27998
Exosc5
exosome component 5 [Source:MGI Symbol;Acc...
50911
50911
Exosc9
exosome component 9 [Source:MGI Symbol;Acc...
50912
50912
Exosc10
exosome component 10 [Source:MGI Symbol;Ac...
66362
66362
Exosc3
exosome component 3 [Source:MGI Symbol;Acc...
66446
66446
Exosc7
exosome component 7 [Source:MGI Symbol;Acc...
66583
66583
Exosc1
exosome component 1 [Source:MGI Symbol;Acc...
67459
67459
Nvl
nuclear VCP-like [Source:MGI Symbol;Acc:MG...
68533
68533
Mphosph6
M phase phosphoprotein 6 [Source:MGI Symbo...
69639
69639
Exosc8
exosome component 8 [Source:MGI Symbol;Acc...
72198
72198
Mtrex
Mtr4 exosome RNA helicase [Source:MGI Symb...
72544
72544
Exosc6
exosome component 6 [Source:MGI Symbol;Acc...
72662
72662
Dis3
DIS3 homolog, exosome endoribonuclease and...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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