Mouse Gene Set: GOCC_MRE11_COMPLEX
For the Human gene set with the same name, see GOCC_MRE11_COMPLEX
Standard name
GOCC_MRE11_COMPLEX
Systematic name
MM12054
Brief description
Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. [GOC:mah, GOC:vw, PMID:11988766, PMID:17674145]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0030870
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0030870
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 5 genes
Show members
(show 5 source identifiers mapped to 5 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
17535
17535
Mre11a
MRE11A homolog A, double strand break repair n...
19360
19360
Rad50
RAD50 double strand break repair protein [Sour...
20684
20684
Sp100
nuclear antigen Sp100 [Source:MGI Symbol;Acc:M...
27354
27354
Nbn
nibrin [Source:MGI Symbol;Acc:MGI:1351625]
68067
68067
Mrnip
MRN complex interacting protein [Source:MGI Sy...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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