Mouse Gene Set: GOCC_MHC_CLASS_I_PEPTIDE_LOADING_COMPLEX
For the Human gene set with the same name, see GOCC_MHC_CLASS_I_PEPTIDE_LOADING_COMPLEX
Standard name
GOCC_MHC_CLASS_I_PEPTIDE_LOADING_COMPLEX
Systematic name
MM12309
Brief description
A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. [GOC:jl, PMID:10631934]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0042824
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0042824
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 15 genes
Show members
(show 15 source identifiers mapped to 15 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
110557
110557
H2-Q6
histocompatibility 2, Q region locus 6 [Sour...
12010
12010
B2m
beta-2 microglobulin [Source:MGI Symbol;Acc:...
12317
12317
Calr
calreticulin [Source:MGI Symbol;Acc:MGI:88252]
14827
14827
Pdia3
protein disulfide isomerase associated 3 [So...
14964
14964
H2-D1
histocompatibility 2, D region locus 1 [Sour...
14972
14972
H2-K1
histocompatibility 2, K1, K region [Source:M...
15006
15006
H2-Q1
histocompatibility 2, Q region locus 1 [Sour...
15007
15007
H2-Q10
histocompatibility 2, Q region locus 10 [Sou...
15013
15013
H2-Q2
histocompatibility 2, Q region locus 2 [Sour...
15015
15015
H2-Q4
histocompatibility 2, Q region locus 4 [Sour...
15018
15018
H2-Q7
histocompatibility 2, Q region locus 7 [Sour...
213233
213233
Tapbpl
TAP binding protein-like [Source:MGI Symbol;...
21354
21354
Tap1
transporter 1, ATP-binding cassette, sub-fam...
21355
21355
Tap2
transporter 2, ATP-binding cassette, sub-fam...
21356
21356
Tapbp
TAP binding protein [Source:MGI Symbol;Acc:M...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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