Mouse Gene Set: GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX
For the Human gene set with the same name, see GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX
Standard name
GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX
Systematic name
MM17427
Brief description
A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV. [GOC:jl, GOC:mah, PMID:10854421, PMID:12235392, PMID:17072889]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0005958
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0005958
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Further investigate
these 6 genes
Show members
(show 6 source identifiers mapped to 6 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
108138
108138
Xrcc4
X-ray repair complementing defective repair i...
14375
14375
Xrcc6
X-ray repair complementing defective repair i...
19090
19090
Prkdc
protein kinase, DNA activated, catalytic poly...
22596
22596
Xrcc5
X-ray repair complementing defective repair i...
319583
319583
Lig4
ligase IV, DNA, ATP-dependent [Source:MGI Sym...
75570
75570
Nhej1
non-homologous end joining factor 1 [Source:M...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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