Mouse Gene Set: GOCC_DEATH_INDUCING_SIGNALING_COMPLEX
For the Human gene set with the same name, see GOCC_DEATH_INDUCING_SIGNALING_COMPLEX
Standard name
GOCC_DEATH_INDUCING_SIGNALING_COMPLEX
Systematic name
MM12099
Brief description
A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10. [GOC:mtg_apoptosis, PMID:12628743, PMID:12655293, PMID:8521815]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0031264
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0031264
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 7 genes
Show members
(show 7 source identifiers mapped to 7 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
12367
12367
Casp3
caspase 3 [Source:MGI Symbol;Acc:MGI:107739]
12370
12370
Casp8
caspase 8 [Source:MGI Symbol;Acc:MGI:1261423]
12633
12633
Cflar
CASP8 and FADD-like apoptosis regulator [Sou...
14082
14082
Fadd
Fas associated via death domain [Source:MGI ...
14102
14102
Fas
Fas cell surface death receptor [Source:MGI ...
19766
19766
Ripk1
receptor (TNFRSF)-interacting serine-threoni...
79201
79201
Tnfrsf23
tumor necrosis factor receptor superfamily, ...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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