Mouse Gene Set: GOCC_BRCA1_C_COMPLEX
For the Human gene set with the same name, see GOCC_BRCA1_C_COMPLEX
Standard name
GOCC_BRCA1_C_COMPLEX
Systematic name
MM12442
Brief description
A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. [GOC:mah, PMID:15485915, PMID:16391231]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0070533
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0070533
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 6 genes
Show members
(show 6 source identifiers mapped to 6 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
12021
12021
Bard1
BRCA1 associated RING domain 1 [Source:MGI S...
12189
12189
Brca1
breast cancer 1, early onset [Source:MGI Sym...
17535
17535
Mre11a
MRE11A homolog A, double strand break repair...
19360
19360
Rad50
RAD50 double strand break repair protein [So...
225182
225182
Rbbp8
retinoblastoma binding protein 8, endonuclea...
27354
27354
Nbn
nibrin [Source:MGI Symbol;Acc:MGI:1351625]
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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