Mouse Gene Set: GOCC_BETA_CATENIN_DESTRUCTION_COMPLEX
For the Human gene set with the same name, see GOCC_BETA_CATENIN_DESTRUCTION_COMPLEX
Standard name
GOCC_BETA_CATENIN_DESTRUCTION_COMPLEX
Systematic name
MM12055
Brief description
A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. [PMID:14600025]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0030877
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0030877
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 13 genes
Show members
(show 13 source identifiers mapped to 13 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
11789
11789
Apc
APC, WNT signaling pathway regulator [Sour...
12005
12005
Axin1
axin 1 [Source:MGI Symbol;Acc:MGI:1096327]
12006
12006
Axin2
axin 2 [Source:MGI Symbol;Acc:MGI:1270862]
12301
12301
Cacybp
calcyclin binding protein [Source:MGI Symb...
12387
12387
Ctnnb1
catenin beta 1 [Source:MGI Symbol;Acc:MGI:...
20437
20437
Siah1a
siah E3 ubiquitin protein ligase 1A [Sourc...
20438
20438
Siah1b
siah E3 ubiquitin protein ligase 1B [Sourc...
23805
23805
Apc2
APC regulator of WNT signaling pathway 2 [...
56637
56637
Gsk3b
glycogen synthase kinase 3 beta [Source:MG...
59036
59036
Dact1
dishevelled-binding antagonist of beta-cat...
606496
606496
Gsk3a
glycogen synthase kinase 3 alpha [Source:M...
67087
67087
Ctnnbip1
catenin beta interacting protein 1 [Source...
93687
93687
Csnk1a1
casein kinase 1, alpha 1 [Source:MGI Symbo...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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