Mouse Gene Set: GOCC_ALPHA_KETOACID_DEHYDROGENASE_COMPLEX

For the Human gene set with the same name, see GOCC_ALPHA_KETOACID_DEHYDROGENASE_COMPLEX

Standard name GOCC_ALPHA_KETOACID_DEHYDROGENASE_COMPLEX
Systematic name MM12381
Brief description A multi-enzyme complex that catalyzes the oxidative decarboxylation of an alpha-ketoacid - pyruvate, a branched-chain alpha-ketoacid or alpha-ketoglutarate (also known as 2-oxoglutarate). The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: a dihydrolipoyl transacylase (E2) forms the core of the complex, with an alpha-ketoacid dehydrogenase (E1) and a dihydrolipoamide dehydrogenase (E3) attached through non-covalent bonds. The E1 and E2 components are specific to different alpha-ketoacid dehydrogenase complexes, whereas the E3 component is the same. Additional proteins may also be present. [GOC:mah, PMID:10745006]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0045240
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0045240
Filtered by similarity ?
Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Mouse_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
Mouse Transcriptomic BodyMap compendium

Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query Further investigate these 16 genes
Show members (show 16 source identifiers mapped to 16 genes)
Version history 2024.1.Mm: Renamed from GOCC_DIHYDROLIPOYL_DEHYDROGENASE_COMPLEX. Updated to GO Release 2024-04-24.

See MSigDB license terms here. Please note that certain gene sets have special access terms.