Mouse Gene Set: GOBP_R_LOOP_PROCESSING
For the Human gene set with the same name, see GOBP_R_LOOP_PROCESSING
Standard name
GOBP_R_LOOP_PROCESSING
Systematic name
MM16289
Brief description
A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability. [PMID:27252122, PMID:28790157, PMID:33986538]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0062176
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0062176
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 9 genes
Show members
(show 9 source identifiers mapped to 9 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
17535
17535
Mre11a
MRE11A homolog A, double strand break repai...
19360
19360
Rad50
RAD50 double strand break repair protein [S...
20817
20817
Srpk2
serine/arginine-rich protein specific kinas...
209011
209011
Sirt7
sirtuin 7 [Source:MGI Symbol;Acc:MGI:2385849]
27354
27354
Nbn
nibrin [Source:MGI Symbol;Acc:MGI:1351625]
408022
408022
Primpol
primase and polymerase (DNA-directed) [Sour...
54446
54446
Nfat5
nuclear factor of activated T cells 5 [Sour...
56200
56200
Ddx21
DExD box helicase 21 [Source:MGI Symbol;Acc...
74351
74351
Ddx23
DEAD box helicase 23 [Source:MGI Symbol;Acc...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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