Mouse Gene Set: GOBP_NON_CANONICAL_NF_KAPPAB_SIGNAL_TRANSDUCTION

For the Human gene set with the same name, see GOBP_NON_CANONICAL_NF_KAPPAB_SIGNAL_TRANSDUCTION

Standard name GOBP_NON_CANONICAL_NF_KAPPAB_SIGNAL_TRANSDUCTION
Systematic name MM7298
Brief description An intracellular signaling cassette characterized by the NIK-dependent processing and activation of NF-kappaB. Begins with activation of the NF-kappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-kappa B2 protein (p100) leading to p100 processing and release of an active NF-kappaB (p52). The non-canonical NF-kappaB signaling pathway is generally activated by ligands of the TNF receptor superfamily, including lymphotoxin beta (LTB), CD40, OX40, RANK, TWEAK and B cell-activating factor (BAFF). [GOC:bf, GOC:mg2, GOC:signaling, GOC:vs, PMID:11239468, PMID:15140882, PMID:34659217]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0038061
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0038061
Filtered by similarity ?
Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Mouse_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
Mouse Transcriptomic BodyMap compendium

Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query Further investigate these 125 genes
Show members (show 125 source identifiers mapped to 125 genes)
Version history 2024.1.Mm: Updated to GO Release 2024-04-24.

See MSigDB license terms here. Please note that certain gene sets have special access terms.