Mouse Gene Set: GOBP_NECROPTOTIC_SIGNALING_PATHWAY
For the Human gene set with the same name, see GOBP_NECROPTOTIC_SIGNALING_PATHWAY
Standard name
GOBP_NECROPTOTIC_SIGNALING_PATHWAY
Systematic name
MM10288
Brief description
The series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered. [GOC:mtg_apoptosis, PMID:20823910]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0097527
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0097527
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
Download gene set
format: grp | gmt | xml | json | TSV metadata
Compute overlaps ?
(show collections to investigate for overlap with this gene set)
Compendia expression profiles ?
NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds )
Mouse Transcriptomic BodyMap compendium
Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query
Further investigate
these 9 genes
Show members
(show 9 source identifiers mapped to 9 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
14082
14082
Fadd
Fas associated via death domain [Source:MG...
14102
14102
Fas
Fas cell surface death receptor [Source:MG...
14103
14103
Fasl
Fas ligand [Source:MGI Symbol;Acc:MGI:99255]
142980
142980
Tlr3
toll-like receptor 3 [Source:MGI Symbol;Ac...
19766
19766
Ripk1
receptor (TNFRSF)-interacting serine-threo...
21926
21926
Tnf
tumor necrosis factor [Source:MGI Symbol;A...
56532
56532
Ripk3
receptor-interacting serine-threonine kina...
74568
74568
Mlkl
mixed lineage kinase domain-like [Source:M...
79201
79201
Tnfrsf23
tumor necrosis factor receptor superfamily...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
See MSigDB license terms here . Please note that certain gene sets
have special access terms.