Mouse Gene Set: GOBP_MDA_5_SIGNALING_PATHWAY
For the Human gene set with the same name, see GOBP_MDA_5_SIGNALING_PATHWAY
Standard name
GOBP_MDA_5_SIGNALING_PATHWAY
Systematic name
MM7328
Brief description
The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. [GOC:bf, PMID:19620789, PMID:33087405]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0039530
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0039530
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 8 genes
Show members
(show 8 source identifiers mapped to 8 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
12261
12261
C1qbp
complement component 1, q subcomponent bind...
225913
225913
Tkfc
triokinase, FMN cyclase [Source:MGI Symbol;...
234311
234311
Ddx60
DExD/H box helicase 60 [Source:MGI Symbol;A...
246727
246727
Oas3
2'-5' oligoadenylate synthetase 3 [Source:M...
66878
66878
Riok3
RIO kinase 3 [Source:MGI Symbol;Acc:MGI:191...
71586
71586
Ifih1
interferon induced with helicase C domain 1...
80861
80861
Dhx58
DExH-box helicase 58 [Source:MGI Symbol;Acc...
81702
81702
Ankrd17
ankyrin repeat domain 17 [Source:MGI Symbol...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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