Mouse Gene Set: GOBP_I_KAPPAB_PHOSPHORYLATION
For the Human gene set with the same name, see GOBP_I_KAPPAB_PHOSPHORYLATION
Standard name
GOBP_I_KAPPAB_PHOSPHORYLATION
Systematic name
MM5041
Brief description
The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. [GOC:bf, GOC:jl, PMID:21772278, PMID:7594468]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0007252
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0007252
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 17 genes
Show members
(show 17 source identifiers mapped to 17 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
111173
111173
Erc1
ELKS/RAB6-interacting/CAST family member 1 [...
11651
11651
Akt1
thymoma viral proto-oncogene 1 [Source:MGI S...
12675
12675
Chuk
conserved helix-loop-helix ubiquitous kinase...
13051
13051
Cx3cr1
C-X3-C motif chemokine receptor 1 [Source:MG...
142980
142980
Tlr3
toll-like receptor 3 [Source:MGI Symbol;Acc:...
16150
16150
Ikbkb
inhibitor of kappaB kinase beta [Source:MGI ...
170743
170743
Tlr7
toll-like receptor 7 [Source:MGI Symbol;Acc:...
19261
19261
Sirpa
signal-regulatory protein alpha [Source:MGI ...
20210
20210
Saa3
serum amyloid A 3 [Source:MGI Symbol;Acc:MGI...
20312
20312
Cx3cl1
C-X3-C motif chemokine ligand 1 [Source:MGI ...
21898
21898
Tlr4
toll-like receptor 4 [Source:MGI Symbol;Acc:...
21926
21926
Tnf
tumor necrosis factor [Source:MGI Symbol;Acc...
234779
234779
Plcg2
phospholipase C, gamma 2 [Source:MGI Symbol;...
24088
24088
Tlr2
toll-like receptor 2 [Source:MGI Symbol;Acc:...
26409
26409
Map3k7
mitogen-activated protein kinase kinase kina...
30940
30940
Usp25
ubiquitin specific peptidase 25 [Source:MGI ...
77006
77006
Ddrgk1
DDRGK domain containing 1 [Source:MGI Symbol...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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