Mouse Gene Set: GOBP_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_HYPOXIA
For the Human gene set with the same name, see GOBP_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_HYPOXIA
Standard name
GOBP_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_HYPOXIA
Systematic name
MM11366
Brief description
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered. [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, PMID:20436456]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:1990144
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:1990144
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
Download gene set
format: grp | gmt | xml | json | TSV metadata
Compute overlaps ?
(show collections to investigate for overlap with this gene set)
Compendia expression profiles ?
NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds )
Mouse Transcriptomic BodyMap compendium
Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query
Further investigate
these 13 genes
Show members
(show 13 source identifiers mapped to 13 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
110213
110213
Tmbim6
transmembrane BAX inhibitor motif containing...
11909
11909
Atf2
activating transcription factor 2 [Source:MG...
12176
12176
Bnip3
BCL2/adenovirus E1B interacting protein 3 [S...
12282
12282
Hyou1
hypoxia up-regulated 1 [Source:MGI Symbol;Ac...
13806
13806
Eno1
enolase 1, alpha non-neuron [Source:MGI Symb...
22059
22059
Trp53
transformation related protein 53 [Source:MG...
22289
22289
Kdm6a
lysine (K)-specific demethylase 6A [Source:M...
26395
26395
Map2k1
mitogen-activated protein kinase kinase 1 [S...
433182
433182
Eno1b
enolase 1B, retrotransposed [Source:MGI Symb...
68943
68943
Pink1
PTEN induced putative kinase 1 [Source:MGI S...
68949
68949
Zfas1
zinc finger, NFX1-type containing 1, antisen...
74769
74769
Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kina...
78688
78688
Nol3
nucleolar protein 3 (apoptosis repressor wit...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
See MSigDB license terms here . Please note that certain gene sets
have special access terms.