Mouse Gene Set: GOBP_ERBB2_SIGNALING_PATHWAY
For the Human gene set with the same name, see GOBP_ERBB2_SIGNALING_PATHWAY
Standard name
GOBP_ERBB2_SIGNALING_PATHWAY
Systematic name
MM7310
Brief description
The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB2 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair. [GOC:jc, PMID:16460914, Reactome:R-HSA-1227986]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0038128
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0038128
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 23 genes
Show members
(show 23 source identifiers mapped to 23 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
100042150
100042150
Nrg2
neuregulin 2 [Source:MGI Symbol;Acc:MG...
110157
110157
Raf1
v-raf-leukemia viral oncogene 1 [Sourc...
11839
11839
Areg
amphiregulin [Source:MGI Symbol;Acc:MG...
12223
12223
Btc
betacellulin, epidermal growth factor ...
13645
13645
Egf
epidermal growth factor [Source:MGI Sy...
13649
13649
Egfr
epidermal growth factor receptor [Sour...
13866
13866
Erbb2
erb-b2 receptor tyrosine kinase 2 [Sou...
13867
13867
Erbb3
erb-b2 receptor tyrosine kinase 3 [Sou...
13869
13869
Erbb4
erb-b2 receptor tyrosine kinase 4 [Sou...
13874
13874
Ereg
epiregulin [Source:MGI Symbol;Acc:MGI:...
14784
14784
Grb2
growth factor receptor bound protein 2...
15200
15200
Hbegf
heparin-binding EGF-like growth factor...
15461
15461
Hras
Harvey rat sarcoma virus oncogene [Sou...
17926
17926
Myoc
myocilin [Source:MGI Symbol;Acc:MGI:12...
19279
19279
Ptprr
protein tyrosine phosphatase receptor ...
20662
20662
Sos1
SOS Ras/Rac guanine nucleotide exchang...
211323
211323
Nrg1
neuregulin 1 [Source:MGI Symbol;Acc:MG...
21802
21802
Tgfa
transforming growth factor alpha [Sour...
26395
26395
Map2k1
mitogen-activated protein kinase kinas...
26396
26396
Map2k2
mitogen-activated protein kinase kinas...
26413
26413
Mapk1
mitogen-activated protein kinase 1 [So...
26417
26417
Mapk3
mitogen-activated protein kinase 3 [So...
70568
70568
Cpne3
copine III [Source:MGI Symbol;Acc:MGI:...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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