Mouse Gene Set: GOBP_ERBB2_EGFR_SIGNALING_PATHWAY
For the Human gene set with the same name, see GOBP_ERBB2_EGFR_SIGNALING_PATHWAY
Standard name
GOBP_ERBB2_EGFR_SIGNALING_PATHWAY
Systematic name
MM7314
Brief description
The series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR. [GOC:signaling, PMID:16460914, Reactome:R-HSA-1963589]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0038134
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0038134
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
Download gene set
format: grp | gmt | xml | json | TSV metadata
Compute overlaps ?
(show collections to investigate for overlap with this gene set)
Compendia expression profiles ?
NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds )
Mouse Transcriptomic BodyMap compendium
Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query
Further investigate
these 8 genes
Show members
(show 8 source identifiers mapped to 8 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
11839
11839
Areg
amphiregulin [Source:MGI Symbol;Acc:MGI:88068]
12223
12223
Btc
betacellulin, epidermal growth factor family me...
13645
13645
Egf
epidermal growth factor [Source:MGI Symbol;Acc:...
13649
13649
Egfr
epidermal growth factor receptor [Source:MGI Sy...
13866
13866
Erbb2
erb-b2 receptor tyrosine kinase 2 [Source:MGI S...
13874
13874
Ereg
epiregulin [Source:MGI Symbol;Acc:MGI:107508]
15200
15200
Hbegf
heparin-binding EGF-like growth factor [Source:...
21802
21802
Tgfa
transforming growth factor alpha [Source:MGI Sy...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
See MSigDB license terms here . Please note that certain gene sets
have special access terms.