Mouse Gene Set: GOBP_EPITHELIAL_TO_MESENCHYMAL _TRANSITION_INVOLVED_IN_ENDOCARDIAL _CUSHION_FORMATION
For the Human gene set with the same name, see GOBP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION
Standard name
GOBP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION
Systematic name
MM4489
Brief description
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion. [GOC:mtg_heart]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0003198
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0003198
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Further investigate
these 18 genes
Show members
(show 18 source identifiers mapped to 18 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
12159
12159
Bmp4
bone morphogenetic protein 4 [Source:MGI Symb...
13805
13805
Eng
endoglin [Source:MGI Symbol;Acc:MGI:95392]
14179
14179
Fgf8
fibroblast growth factor 8 [Source:MGI Symbol...
15213
15213
Hey1
hairy/enhancer-of-split related with YRPW mot...
17128
17128
Smad4
SMAD family member 4 [Source:MGI Symbol;Acc:M...
17701
17701
Msx1
msh homeobox 1 [Source:MGI Symbol;Acc:MGI:97168]
17702
17702
Msx2
msh homeobox 2 [Source:MGI Symbol;Acc:MGI:97169]
18128
18128
Notch1
notch 1 [Source:MGI Symbol;Acc:MGI:97363]
19664
19664
Rbpj
recombination signal binding protein for immu...
20583
20583
Snai2
snail family zinc finger 2 [Source:MGI Symbol...
20613
20613
Snai1
snail family zinc finger 1 [Source:MGI Symbol...
21803
21803
Tgfb1
transforming growth factor, beta 1 [Source:MG...
21808
21808
Tgfb2
transforming growth factor, beta 2 [Source:MG...
21809
21809
Tgfb3
transforming growth factor, beta 3 [Source:MG...
21812
21812
Tgfbr1
transforming growth factor, beta receptor I [...
21813
21813
Tgfbr2
transforming growth factor, beta receptor II ...
56198
56198
Heyl
hairy/enhancer-of-split related with YRPW mot...
67888
67888
Tmem100
transmembrane protein 100 [Source:MGI Symbol;...
Version history
2026.1.Mm: Updated to GO Release 2025-10-10.
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The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .