Mouse Gene Set: GOBP_CGAS_STING_SIGNALING_PATHWAY
For the Human gene set with the same name, see GOBP_CGAS_STING_SIGNALING_PATHWAY
Standard name
GOBP_CGAS_STING_SIGNALING_PATHWAY
Systematic name
MM17377
Brief description
The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING. [PMID:27648547, PMID:34261127, PMID:34261128]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0140896
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0140896
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 18 genes
Show members
(show 18 source identifiers mapped to 18 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
11545
11545
Parp1
poly (ADP-ribose) polymerase family, member...
11651
11651
Akt1
thymoma viral proto-oncogene 1 [Source:MGI ...
15944
15944
Irgm1
immunity-related GTPase family M member 1 [...
16145
16145
Igtp
interferon gamma induced GTPase [Source:MGI...
18521
18521
Pcbp2
poly(rC) binding protein 2 [Source:MGI Symb...
19090
19090
Prkdc
protein kinase, DNA activated, catalytic po...
20877
20877
Aurkb
aurora kinase B [Source:MGI Symbol;Acc:MGI:...
208884
208884
Zdhhc9
zinc finger, DHHC domain containing 9 [Sour...
214763
214763
Cgas
cyclic GMP-AMP synthase [Source:MGI Symbol;...
22040
22040
Trex1
three prime repair exonuclease 1 [Source:MG...
226791
226791
Lyplal1
lysophospholipase-like 1 [Source:MGI Symbol...
23825
23825
Banf1
BAF nuclear assembly factor 1 [Source:MGI S...
26409
26409
Map3k7
mitogen-activated protein kinase kinase kin...
503610
503610
Zdhhc18
zinc finger, DHHC domain containing 18 [Sou...
54396
54396
Irgm2
immunity-related GTPase family M member 2 [...
66513
66513
Tab1
TGF-beta activated kinase 1/MAP3K7 binding ...
67857
67857
Ppp6c
protein phosphatase 6, catalytic subunit [S...
72512
72512
Sting1
stimulator of interferon response cGAMP int...
Version history
2024.1.Mm: Updated to GO Release 2024-04-24.
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