Mouse Gene Set: DURAND_STROMA_S_UP

For the Human gene set with the same name, see DURAND_STROMA_S_UP

Standard name DURAND_STROMA_S_UP
Systematic name MM1083
Brief description Genes up-regulated in the HSC supportive stromal cell lines.
Full description or abstract Stromal cell lines represent an exceptional tool to study the role on the microenvironment on hematopoietic stem cell (HSC) activity. We have compared the expression profile of HSC supportive vs non-supportive stromal lines generated from different hematopoietic tissues in the mouse, i.e the aorta-gonad-mesonephros (AGM) region, the fetal liver and the adult bone marrow, sequentially activated during development. In this study, six stromal lines were used with one HSC supportive and one non-supportive for each tissue (triplicate samples for each stromal line). We used Mouse Gene 1.0 ST microrrays in combination with GSEA and statistical analysis to identify lists of genes that segregate HSC supportive from non-supportive stromal lines.
Collection M2: Curated
      CGP: Chemical and Genetic Perturbations
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Source species Mus musculus
Contributed by Charles Durand (Pierre and Marie Curie University)
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identifier namespace		 Mouse_NCBI_Gene_ID
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Version history 2022.1.Mm: First Introduced.

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