Mouse Gene Set: BIOCARTA_TNFR2_PATHWAY
For the Human gene set with the same name, see BIOCARTA_TNFR2_PATHWAY
Standard name
BIOCARTA_TNFR2_PATHWAY
Systematic name
MM1517
Brief description
TNFR2 Signaling Pathway
Full description or abstract
TNFR2 is the receptor for the 171 amino acid 19 kD TNF(beta) (a.k.a. lymphotoxin). TNF(beta) is produced by activated lymphocytes and can be cytotoxic to many tumor and other cells. In neutrophils, endothelial cells and osteoclasts TNF(beta) can lead to activation while in many other cell types it can lead to increased expression of MHC and adhesion molecules.
Collection
M2: Curated CP: Canonical Pathways CP:BIOCARTA: BioCarta Pathways
Source publication
Exact source
Related gene sets
External links
https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_tnfr2Pathway.gif
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Source species
Mus musculus
Contributed by
BioCarta
Source platform or identifier namespace
MOUSE_SEQ_ACCESSION
Dataset references
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Further investigate
these 17 genes
Show members
(show 17 source identifiers mapped to 17 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
NM_001048206
22031
Traf3
TNF receptor-associated factor 3 [So...
NM_001159774
16150
Ikbkb
inhibitor of kappaB kinase beta [Sou...
NM_001161422
16151
Ikbkg
inhibitor of kappaB kinase gamma [So...
NM_001162410
12675
Chuk
conserved helix-loop-helix ubiquitou...
NM_001166402
21929
Tnfaip3
tumor necrosis factor, alpha-induced...
NM_008689
18033
Nfkb1
nuclear factor of kappa light polype...
NM_009045
19697
Rela
v-rel reticuloendotheliosis viral on...
NM_009068
19766
Ripk1
receptor (TNFRSF)-interacting serine...
NM_009421
22029
Traf1
TNF receptor-associated factor 1 [So...
NM_009422
22030
Traf2
TNF receptor-associated factor 2 [So...
NM_010907
18035
Nfkbia
nuclear factor of kappa light polype...
NM_011529
21353
Tank
TRAF family member-associated Nf-kap...
NM_011610
21938
Tnfrsf1b
tumor necrosis factor receptor super...
NM_011945
26401
Map3k1
mitogen-activated protein kinase kin...
NM_013642
19252
Dusp1
dual specificity phosphatase 1 [Sour...
NM_016896
53859
Map3k14
mitogen-activated protein kinase kin...
NM_026079
230233
Elp1
elongator complex protein 1 [Source:...
Version history
2022.1.Mm: First Introduced.
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