Mouse Gene Set: BIOCARTA_STEM_PATHWAY
For the Human gene set with the same name, see BIOCARTA_STEM_PATHWAY
Standard name
BIOCARTA_STEM_PATHWAY
Systematic name
MM1471
Brief description
Regulation of hematopoiesis by cytokines
Full description or abstract
The process of hematopoesis is regulated by various cytokines. The combination of cytokines stimulates the proliferation and/or differentiation of the various hematopoietic cell types. Bone marrow stromal cells are the major source of hematopoietic cytokines in the non-infecteous state. In the presence of infection, cytokines produced by activated macrophages and TH cells induce hematopoietic activity. The induction by cytokines results in rapid expansion of the population of white blood cells to fight infection. The specific cytokines that affect a step of cell differentiation are placed adjacent to the arrow representing that step. Lines with '?' indicate likely, but still hypothetical pathways.
Collection
M2: Curated CP: Canonical Pathways CP:BIOCARTA: BioCarta Pathways
Source publication
Exact source
Related gene sets
External links
https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_stemPathway.gif
Filtered by similarity ?
Source species
Mus musculus
Contributed by
BioCarta
Source platform or identifier namespace
MOUSE_SEQ_ACCESSION
Dataset references
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Further investigate
these 14 genes
Show members
(show 14 source identifiers mapped to 14 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
NM_001113530
12977
Csf1
colony stimulating factor 1 (macrophage) ...
NM_007942
13856
Epo
erythropoietin [Source:MGI Symbol;Acc:MGI...
NM_008350
16156
Il11
interleukin 11 [Source:MGI Symbol;Acc:MGI...
NM_008366
16183
Il2
interleukin 2 [Source:MGI Symbol;Acc:MGI:...
NM_008371
16196
Il7
interleukin 7 [Source:MGI Symbol;Acc:MGI:...
NM_008373
16198
Il9
interleukin 9 [Source:MGI Symbol;Acc:MGI:...
NM_009857
12525
Cd8a
CD8 subunit alpha [Source:MGI Symbol;Acc:...
NM_009969
12981
Csf2
colony stimulating factor 2 (granulocyte-...
NM_009971
12985
Csf3
colony stimulating factor 3 (granulocyte)...
NM_010556
16187
Il3
interleukin 3 [Source:MGI Symbol;Acc:MGI:...
NM_010558
16191
Il5
interleukin 5 [Source:MGI Symbol;Acc:MGI:...
NM_013488
12504
Cd4
CD4 antigen [Source:MGI Symbol;Acc:MGI:88...
NM_021283
16189
Il4
interleukin 4 [Source:MGI Symbol;Acc:MGI:...
NM_031168
16193
Il6
interleukin 6 [Source:MGI Symbol;Acc:MGI:...
Version history
2022.1.Mm: First Introduced.
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