Mouse Gene Set: BIOCARTA_IL4_PATHWAY
For the Human gene set with the same name, see BIOCARTA_IL4_PATHWAY
Standard name
BIOCARTA_IL4_PATHWAY
Systematic name
MM1413
Brief description
IL 4 signaling pathway
Full description or abstract
Interleukin 4 (IL-4) is a cytokine that can lead to development of Th2 cells. The 140 kD IL-4 Receptor (CD124) is found on many cell types, even those of non-hematopoietic origen. The receptor is formed from two chains: IL-4R(alpha) and the IL-2R gamma chain (CD132). Primary signaling is through the JAK/Stat6 pathway and MAPKs.
Collection
M2: Curated CP: Canonical Pathways CP:BIOCARTA: BioCarta Pathways
Source publication
Exact source
Related gene sets
External links
https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_il4Pathway.gif
Filtered by similarity ?
Source species
Mus musculus
Contributed by
BioCarta
Source platform or identifier namespace
MOUSE_SEQ_ACCESSION
Dataset references
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Advanced query
Further investigate
these 11 genes
Show members
(show 15 source identifiers mapped to 11 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
AK053930
72508
Rps6kb1
ribosomal protein S6 kinase, polypepti...
AK143689
72508
Rps6kb1
ribosomal protein S6 kinase, polypepti...
AK155158
20416
Shc1
src homology 2 domain-containing trans...
BG694441
BU515502
NM_001008700
16190
Il4ra
interleukin 4 receptor, alpha [Source:...
NM_001165894
11651
Akt1
thymoma viral proto-oncogene 1 [Source...
NM_001190830
16453
Jak3
Janus kinase 3 [Source:MGI Symbol;Acc:...
NM_008163
14784
Grb2
growth factor receptor bound protein 2...
NM_009284
20852
Stat6
signal transducer and activator of tra...
NM_010570
16367
Irs1
insulin receptor substrate 1 [Source:M...
NM_013563
16186
Il2rg
interleukin 2 receptor, gamma chain [S...
NM_021283
16189
Il4
interleukin 4 [Source:MGI Symbol;Acc:M...
NM_028259
72508
Rps6kb1
ribosomal protein S6 kinase, polypepti...
NM_146145
16451
Jak1
Janus kinase 1 [Source:MGI Symbol;Acc:...
Version history
2022.1.Mm: First Introduced.
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