Mouse Gene Set: BIOCARTA_IL3_PATHWAY
For the Human gene set with the same name, see BIOCARTA_IL3_PATHWAY
Standard name
BIOCARTA_IL3_PATHWAY
Systematic name
MM1412
Brief description
IL 3 signaling pathway
Full description or abstract
Interleukin-3 promotes the proliferation and differentiation of hematopoietic cells through binding to its receptor. The receptor for IL-3 is a heterodimer with a ligand-specific alpha chain (70 kD, CD123) and a common beta chain (shared with IL-5 and GM-CSF). Signaling is believed to be primarily through Stat5 and the MAPK pathways.
Collection
M2: Curated CP: Canonical Pathways CP:BIOCARTA: BioCarta Pathways
Source publication
Exact source
Related gene sets
External links
https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_il3Pathway.gif
Filtered by similarity ?
Source species
Mus musculus
Contributed by
BioCarta
Source platform or identifier namespace
MOUSE_SEQ_ACCESSION
Dataset references
Download gene set
format: grp | gmt | xml | json | TSV metadata
Compute overlaps ?
(show collections to investigate for overlap with this gene set)
Compendia expression profiles ?
NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds )
Mouse Transcriptomic BodyMap compendium
Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query
Further investigate
these 15 genes
Show members
(show 17 source identifiers mapped to 15 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
AK155158
20416
Shc1
src homology 2 domain-containing trans...
BG694441
BU515502
NM_001048177
16452
Jak2
Janus kinase 2 [Source:MGI Symbol;Acc:...
NM_001113563
20851
Stat5b
signal transducer and activator of tra...
NM_001164062
20850
Stat5a
signal transducer and activator of tra...
NM_007780
12983
Csf2rb
colony stimulating factor 2 receptor, ...
NM_008163
14784
Grb2
growth factor receptor bound protein 2...
NM_008284
15461
Hras
Harvey rat sarcoma virus oncogene [Sou...
NM_008369
16188
Il3ra
interleukin 3 receptor, alpha chain [S...
NM_008927
26395
Map2k1
mitogen-activated protein kinase kinas...
NM_009231
20662
Sos1
SOS Ras/Rac guanine nucleotide exchang...
NM_010234
14281
Fos
FBJ osteosarcoma oncogene [Source:MGI ...
NM_010556
16187
Il3
interleukin 3 [Source:MGI Symbol;Acc:M...
NM_011952
26417
Mapk3
mitogen-activated protein kinase 3 [So...
NM_013545
15170
Ptpn6
protein tyrosine phosphatase, non-rece...
NM_029780
110157
Raf1
v-raf-leukemia viral oncogene 1 [Sourc...
Version history
2022.1.Mm: First Introduced.
See MSigDB license terms here . Please note that certain gene sets
have special access terms.