Mouse Gene Set: BIOCARTA_EPO_PATHWAY
For the Human gene set with the same name, see BIOCARTA_EPO_PATHWAY
Standard name
BIOCARTA_EPO_PATHWAY
Systematic name
MM1389
Brief description
EPO Signaling Pathway
Full description or abstract
Erythropoietin functions to increase the number of red blood cells. Thus, it has found utility as a drug for those needing to replenish erythrocytes for a number of reasons. The signaling mechanism includes multimerization of the receptor upon ligand binding, activation of MAPK cascade, and phosphorylation and activation of Stat5.
Collection
M2: Curated CP: Canonical Pathways CP:BIOCARTA: BioCarta Pathways
Source publication
Exact source
Related gene sets
External links
https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_epoPathway.gif
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Source species
Mus musculus
Contributed by
BioCarta
Source platform or identifier namespace
MOUSE_SEQ_ACCESSION
Dataset references
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Further investigate
these 20 genes
Show members
(show 22 source identifiers mapped to 20 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
AK155158
20416
Shc1
src homology 2 domain-containing tran...
BG694441
BU515502
NM_001048177
16452
Jak2
Janus kinase 2 [Source:MGI Symbol;Acc...
NM_001113563
20851
Stat5b
signal transducer and activator of tr...
NM_001164062
20850
Stat5a
signal transducer and activator of tr...
NM_007788
12995
Csnk2a1
casein kinase 2, alpha 1 polypeptide ...
NM_007922
13712
Elk1
ELK1, member of ETS oncogene family [...
NM_007942
13856
Epo
erythropoietin [Source:MGI Symbol;Acc...
NM_008163
14784
Grb2
growth factor receptor bound protein ...
NM_008284
15461
Hras
Harvey rat sarcoma virus oncogene [So...
NM_008927
26395
Map2k1
mitogen-activated protein kinase kina...
NM_009231
20662
Sos1
SOS Ras/Rac guanine nucleotide exchan...
NM_009974
13000
Csnk2a2
casein kinase 2, alpha prime polypept...
NM_010149
13857
Epor
erythropoietin receptor [Source:MGI S...
NM_010234
14281
Fos
FBJ osteosarcoma oncogene [Source:MGI...
NM_010591
16476
Jun
jun proto-oncogene [Source:MGI Symbol...
NM_011952
26417
Mapk3
mitogen-activated protein kinase 3 [S...
NM_013545
15170
Ptpn6
protein tyrosine phosphatase, non-rec...
NM_016700
26419
Mapk8
mitogen-activated protein kinase 8 [S...
NM_021280
18803
Plcg1
phospholipase C, gamma 1 [Source:MGI ...
NM_029780
110157
Raf1
v-raf-leukemia viral oncogene 1 [Sour...
Version history
2022.1.Mm: First Introduced.
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