Mouse Gene Set: BIOCARTA_BCELLSURVIVAL_PATHWAY
For the Human gene set with the same name, see BIOCARTA_BCELLSURVIVAL_PATHWAY
Standard name
BIOCARTA_BCELLSURVIVAL_PATHWAY
Systematic name
MM1353
Brief description
B Cell Survival Pathway
Full description or abstract
Physical interactions between intergrin alpha4beta1 heterodimer expressed on B cells and counter receptors on stroma cells are key mediators of the survival of normal and malignant B cells. Recent data indicate that integrin stimulation increases FBI-1, XIAP, surviving, and CCT4 expression but inhibits Requiem, c-Fos, and caspase 3 and 7 induction.
Collection
M2: Curated CP: Canonical Pathways CP:BIOCARTA: BioCarta Pathways
Source publication
Exact source
Related gene sets
External links
https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_bcellsurvivalPathwa...
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Source species
Mus musculus
Contributed by
BioCarta
Source platform or identifier namespace
MOUSE_SEQ_ACCESSION
Dataset references
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Advanced query
Further investigate
these 16 genes
Show members
(show 20 source identifiers mapped to 16 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
AK011873
12464
Cct4
chaperonin containing TCP1 subunit 4 [...
AK042377
30955
Pik3cg
phosphatidylinositol-4,5-bisphosphate ...
BY720777
CA326503
NM_001024955
18708
Pik3r1
phosphoinositide-3-kinase regulatory s...
NM_001033228
109700
Itga1
integrin alpha 1 [Source:MGI Symbol;Ac...
NM_001146200
30955
Pik3cg
phosphatidylinositol-4,5-bisphosphate ...
NM_001165894
11651
Akt1
thymoma viral proto-oncogene 1 [Source...
NM_007611
12369
Casp7
caspase 7 [Source:MGI Symbol;Acc:MGI:1...
NM_008839
18706
Pik3ca
phosphatidylinositol-4,5-bisphosphate ...
NM_009688
11798
Xiap
X-linked inhibitor of apoptosis [Sourc...
NM_009689
11799
Birc5
baculoviral IAP repeat-containing 5 [S...
NM_009810
12367
Casp3
caspase 3 [Source:MGI Symbol;Acc:MGI:1...
NM_009837
12464
Cct4
chaperonin containing TCP1 subunit 4 [...
NM_010234
14281
Fos
FBJ osteosarcoma oncogene [Source:MGI ...
NM_010578
16412
Itgb1
integrin beta 1 (fibronectin receptor ...
NM_010592
16478
Jund
jun D proto-oncogene [Source:MGI Symbo...
NM_010731
16969
Zbtb7a
zinc finger and BTB domain containing ...
NM_011262
19708
Dpf2
double PHD fingers 2 [Source:MGI Symbo...
NM_020009
56717
Mtor
mechanistic target of rapamycin kinase...
Version history
2022.1.Mm: First Introduced.
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