Mouse Gene Set: BIOCARTA_BARRESTIN_SRC_PATHWAY

For the Human gene set with the same name, see BIOCARTA_BARRESTIN_SRC_PATHWAY

Standard name BIOCARTA_BARRESTIN_SRC_PATHWAY
Systematic name MM1491
Brief description Roles of b-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling
Full description or abstract The binding of -arrestins to agonist-occupied GPCRs coincides with the recruitment of Src family tyrosine kinases, including c-Src, Hck and c-Fgr (Src-TK), to the receptor-arrestin complex. Several signaling events have been reported to involve -arrestin-dependent Src recruitment. These include the regulation of clathrin-dependent 2-adrenergic receptor endocytosis by tyrosine phosphorylation of dynamin, Ras-dependent activation of the ERK1/2 MAP kinase cascade and stimulation of cell proliferation by 2-adrenergic and neurokinin NK1 receptors, and stimulation of chemokine CXCR1 receptor-mediated neutrophil degranulation
Collection M2: Curated
      CP: Canonical Pathways
            CP:BIOCARTA: BioCarta Pathways
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External links https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_bArrestin-srcPathwa...
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Source species Mus musculus
Contributed by BioCarta
Source platform or
identifier namespace		 MOUSE_SEQ_ACCESSION
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Version history 2022.1.Mm: First Introduced.

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