Mouse Gene Set: BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP
For the Human gene set with the same name, see BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP
Standard name
BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP
Systematic name
MM1336
Brief description
Tha authors analyzed RNA sequencing data to investigate the comprehensive transcriptomic landscape of Verteporfin treated Type 1 endometrial cancer cell lines, including HEC-1-A and HEC-1-B.
Full description or abstract
Verteporfin is a porphyrinic photosensitizer clinically used for the photodynamic treatment of age-related macular degeneration. The authors previously tested the efficacy of Verteporfin in endometrial cancer cells and observed cytotoxic and anti-proliferative effects.
Collection
M2: Curated CGP: Chemical and Genetic Perturbations
Source publication
Pubmed 30846786 Authors: Bang LG,Dasari VR,Kim D,Gogoi RP
Exact source
Table 1. Top 20 upregulated genes in HEC-1-A and HEC-1-B cells after VP treatment, ranked by logFC.
Related gene sets
(show 1 additional gene sets from the source publication)
External links
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405995/
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Source species
Homo sapiens
Contributed by
Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
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Advanced query
Further investigate
these 20 genes
Show members
(show 20 source identifiers mapped to 20 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
ADAM9
11502
Adam9
ADAM metallopeptidase domain 9 [Source:MGI...
ANKRD1
107765
Ankrd1
ankyrin repeat domain 1 [Source:MGI Symbol...
APP
11820
App
amyloid beta precursor protein [Source:MGI...
ATP6AP2
70495
Atp6ap2
ATPase, H+ transporting, lysosomal accesso...
COL12A1
12816
Col12a1
collagen, type XII, alpha 1 [Source:MGI Sy...
COL4A2
12827
Col4a2
collagen, type IV, alpha 2 [Source:MGI Sym...
CYR61
16007
Ccn1
cellular communication network factor 1 [S...
DSG2
13511
Dsg2
desmoglein 2 [Source:MGI Symbol;Acc:MGI:11...
EGR1
13653
Egr1
early growth response 1 [Source:MGI Symbol...
GANAB
14376
Ganab
alpha glucosidase 2 alpha neutral subunit ...
GBA
14466
Gba1
glucosylceramidase beta 1 [Source:MGI Symb...
GPC4
14735
Gpc4
glypican 4 [Source:MGI Symbol;Acc:MGI:104902]
ITGAV
16410
Itgav
integrin alpha V [Source:MGI Symbol;Acc:MG...
ITGB4
192897
Itgb4
integrin beta 4 [Source:MGI Symbol;Acc:MGI...
NUP210
54563
Nup210
nucleoporin 210 [Source:MGI Symbol;Acc:MGI...
OS9
216440
Os9
amplified in osteosarcoma [Source:MGI Symb...
SEMA3C
20348
Sema3c
sema domain, immunoglobulin domain (Ig), s...
TFPI2
21789
Tfpi2
tissue factor pathway inhibitor 2 [Source:...
THBS1
21825
Thbs1
thrombospondin 1 [Source:MGI Symbol;Acc:MG...
VCAN
13003
Vcan
versican [Source:MGI Symbol;Acc:MGI:102889]
Version history
2022.1.Mm: First Introduced.
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