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Human Gene Set: WP_TCA_CYCLE_AND_DEFICIENCY_OF_PYRUVATE_DEHYDROGENASE_COMPLEX_PDHC
Standard name
WP_TCA_CYCLE_AND_DEFICIENCY_OF_PYRUVATE_DEHYDROGENASE_COMPLEX_PDHC
Systematic name
M39489
Brief description
TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc)
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:WIKIPATHWAYS: WikiPathways
Source publication
Exact source
WP2453
Related gene sets
External links
https://www.wikipathways.org/instance/WP2453
Filtered by similarity
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Source species
Homo sapiens
Contributed by
WikiPathways
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 16 genes
Gene families
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Categorize
these 16 genes by gene family
Show members
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16 source identifiers mapped to 16 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
1431
1431
CS
citrate synthase [Source:HGNC Symbol;Acc:HGNC:2422]
1737
1737
DLAT
dihydrolipoamide S-acetyltransferase [Source:HGN...
1738
1738
DLD
dihydrolipoamide dehydrogenase [Source:HGNC Symb...
1743
1743
DLST
dihydrolipoamide S-succinyltransferase [Source:H...
2271
2271
FH
fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:...
3417
3417
IDH1
isocitrate dehydrogenase (NADP(+)) 1 [Source:HGN...
3419
3419
IDH3A
isocitrate dehydrogenase (NAD(+)) 3 catalytic su...
4190
4190
MDH1
malate dehydrogenase 1 [Source:HGNC Symbol;Acc:H...
47
47
ACLY
ATP citrate lyase [Source:HGNC Symbol;Acc:HGNC:115]
48
48
ACO1
aconitase 1 [Source:HGNC Symbol;Acc:HGNC:117]
4967
4967
OGDH
oxoglutarate dehydrogenase [Source:HGNC Symbol;A...
5091
5091
PC
pyruvate carboxylase [Source:HGNC Symbol;Acc:HGN...
5105
5105
PCK1
phosphoenolpyruvate carboxykinase 1 [Source:HGNC...
5160
5160
PDHA1
pyruvate dehydrogenase E1 subunit alpha 1 [Sourc...
6389
6389
SDHA
succinate dehydrogenase complex flavoprotein sub...
8801
8801
SUCLG2
succinate-CoA ligase GDP-forming subunit beta [S...
Version history
2024.1.Hs: Updated to WikiPathways Release 20240710
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