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Human Gene Set: WP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS
Standard name
WP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS
Systematic name
M48306
Brief description
RIOK1 and RIOK2 in EGFR- and PI3K-mediated tumorigenesis
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:WIKIPATHWAYS: WikiPathways
Source publication
Exact source
WP3873
Related gene sets
External links
https://www.wikipathways.org/instance/WP3873
Filtered by similarity
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Source species
Homo sapiens
Contributed by
WikiPathways
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 15 genes
Gene families
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Categorize
these 15 genes by gene family
Show members
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show
15 source identifiers mapped to 15 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10000
10000
AKT3
AKT serine/threonine kinase 3 [Source:HGNC ...
1956
1956
EGFR
epidermal growth factor receptor [Source:HG...
207
207
AKT1
AKT serine/threonine kinase 1 [Source:HGNC ...
208
208
AKT2
AKT serine/threonine kinase 2 [Source:HGNC ...
2309
2309
FOXO3
forkhead box O3 [Source:HGNC Symbol;Acc:HGN...
2475
2475
MTOR
mechanistic target of rapamycin kinase [Sou...
253260
253260
RICTOR
RPTOR independent companion of MTOR complex...
5290
5290
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kin...
55781
55781
RIOK2
RIO kinase 2 [Source:HGNC Symbol;Acc:HGNC:1...
5728
5728
PTEN
phosphatase and tensin homolog [Source:HGNC...
6135
6135
RPL11
ribosomal protein L11 [Source:HGNC Symbol;A...
64223
64223
MLST8
MTOR associated protein, LST8 homolog [Sour...
7157
7157
TP53
tumor protein p53 [Source:HGNC Symbol;Acc:H...
79109
79109
MAPKAP1
MAPK associated protein 1 [Source:HGNC Symb...
83732
83732
RIOK1
RIO kinase 1 [Source:HGNC Symbol;Acc:HGNC:1...
Version history
2024.1.Hs: Updated to WikiPathways Release 20240710
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