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Human Gene Set: WP_MODULATION_OF_PI3KAKTMTOR_SIGNALING_BY_BIOACTIVE_SPHINGOLIPIDS
Standard name
WP_MODULATION_OF_PI3KAKTMTOR_SIGNALING_BY_BIOACTIVE_SPHINGOLIPIDS
Systematic name
M45553
Brief description
Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:WIKIPATHWAYS: WikiPathways
Source publication
Exact source
WP5192
Related gene sets
External links
https://www.wikipathways.org/instance/WP5192
Filtered by similarity
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Source species
Homo sapiens
Contributed by
WikiPathways
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 14 genes
Gene families
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Categorize
these 14 genes by gene family
Show members
(
show
15 source identifiers mapped to 14 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10715
10715
CERS1
ceramide synthase 1 [Source:HGNC Symbol;Acc:H...
1901
1901
S1PR1
sphingosine-1-phosphate receptor 1 [Source:HG...
1903
1903
S1PR3
sphingosine-1-phosphate receptor 3 [Source:HG...
207
207
AKT1
AKT serine/threonine kinase 1 [Source:HGNC Sy...
2475
2475
MTOR
mechanistic target of rapamycin kinase [Sourc...
286223
1903
S1PR3
sphingosine-1-phosphate receptor 3 [Source:HG...
3091
3091
HIF1A
hypoxia inducible factor 1 subunit alpha [Sou...
3480
3480
IGF1R
insulin like growth factor 1 receptor [Source...
4790
4790
NFKB1
nuclear factor kappa B subunit 1 [Source:HGNC...
5290
5290
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinas...
5337
5337
PLD1
phospholipase D1 [Source:HGNC Symbol;Acc:HGNC...
56624
56624
ASAH2
N-acylsphingosine amidohydrolase 2 [Source:HG...
56848
56848
SPHK2
sphingosine kinase 2 [Source:HGNC Symbol;Acc:...
64781
64781
CERK
ceramide kinase [Source:HGNC Symbol;Acc:HGNC:...
7248
7248
TSC1
TSC complex subunit 1 [Source:HGNC Symbol;Acc...
Version history
2024.1.Hs: Renamed from WP_MODULATION_OF_PI3K_AKT_MTOR_SIGNALING_BY_BIOACTIVE_SPHINGOLIPIDS. Updated to WikiPathways Release 20240710
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