login
register
GSEA Home
Downloads
Molecular Signatures Database
Documentation
Contact
Team
MSigDB Home
Human Collections
About
Browse
Search
Investigate
Gene Families
Mouse Collections
About
Browse
Search
Investigate
Help
Human Gene Set: SA_FAS_SIGNALING
Standard name
SA_FAS_SIGNALING
Systematic name
M5060
Brief description
The TNF-type receptor Fas induces apoptosis on ligand binding.
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
Source publication
Exact source
Related gene sets
External links
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
SigmaAldrich
Source platform or
identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
?
(
show
collections to investigate for overlap with this gene set)
H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
?
NG-CHM interactive heatmaps
(
Please note that clustering takes a few seconds
)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 9 genes
Gene families
?
Categorize
these 9 genes by gene family
Show members
(
show
9 source identifiers mapped to 9 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
BCL2
596
BCL2
BCL2 apoptosis regulator [Source:HGNC Symbol...
CASP3
836
CASP3
caspase 3 [Source:HGNC Symbol;Acc:HGNC:1504]
CASP8
841
CASP8
caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509]
CFL1
1072
CFL1
cofilin 1 [Source:HGNC Symbol;Acc:HGNC:1874]
CFLAR
8837
CFLAR
CASP8 and FADD like apoptosis regulator [Sou...
P11
6281
S100A10
S100 calcium binding protein A10 [Source:HGN...
PDE6D
5147
PDE6D
phosphodiesterase 6D [Source:HGNC Symbol;Acc...
TNFRSF6
355
FAS
Fas cell surface death receptor [Source:HGNC...
TNFSF6
356
FASLG
Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936]
Version history
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.