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Human Gene Set: REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CASPASE_ACTIVATORS_AND_CASPASES
Standard name
REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CASPASE_ACTIVATORS_AND_CASPASES
Systematic name
M27630
Brief description
TP53 Regulates Transcription of Caspase Activators and Caspases
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-6803207
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-6803207
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 12 genes
Gene families
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Categorize
these 12 genes by gene family
Show members
(
show
12 source identifiers mapped to 12 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000003400
843
CASP10
caspase 10 [Source:HGNC Symbol;Acc:H...
ENSG00000073282
8626
TP63
tumor protein p63 [Source:HGNC Symbo...
ENSG00000078900
7161
TP73
tumor protein p73 [Source:HGNC Symbo...
ENSG00000091106
58484
NLRC4
NLR family CARD domain containing 4 ...
ENSG00000106144
835
CASP2
caspase 2 [Source:HGNC Symbol;Acc:HG...
ENSG00000120868
317
APAF1
apoptotic peptidase activating facto...
ENSG00000137752
834
CASP1
caspase 1 [Source:HGNC Symbol;Acc:HG...
ENSG00000138794
839
CASP6
caspase 6 [Source:HGNC Symbol;Acc:HG...
ENSG00000141510
7157
TP53
tumor protein p53 [Source:HGNC Symbo...
ENSG00000149311
472
ATM
ATM serine/threonine kinase [Source:...
ENSG00000169372
8738
CRADD
CASP2 and RIPK1 domain containing ad...
ENSG00000177595
55367
PIDD1
p53-induced death domain protein 1 [...
Version history
2024.1.Hs: Updated to Reactome v89
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