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Human Gene Set: REACTOME_SOS_MEDIATED_SIGNALLING
Standard name
REACTOME_SOS_MEDIATED_SIGNALLING
Systematic name
M19489
Brief description
SOS-mediated signalling
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-112412
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-112412
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 7 genes
Gene families
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Categorize
these 7 genes by gene family
Show members
(
show
8 source identifiers mapped to 7 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000115904
6654
SOS1
SOS Ras/Rac guanine nucleotide exchange...
ENSG00000133703
3845
KRAS
KRAS proto-oncogene, GTPase [Source:HGN...
ENSG00000169047
3667
IRS1
insulin receptor substrate 1 [Source:HG...
ENSG00000174775
3265
HRAS
HRas proto-oncogene, GTPase [Source:HGN...
ENSG00000177885
2885
GRB2
growth factor receptor bound protein 2 ...
ENSG00000185950
8660
IRS2
insulin receptor substrate 2 [Source:HG...
ENSG00000213281
4893
NRAS
NRAS proto-oncogene, GTPase [Source:HGN...
ENSG00000276536
3265
HRAS
HRas proto-oncogene, GTPase [Source:HGN...
Version history
2024.1.Hs: Updated to Reactome v89
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