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Human Gene Set: REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER
Standard name
REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER
Systematic name
M27202
Brief description
Signaling by NOTCH1 HD Domain Mutants in Cancer
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-2691230
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-2691230
Filtered by similarity
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1 similar pathway(s) from the external resource)
External ID
External Name
R-HSA-2691232
Constitutive Signaling by NOTCH1 HD Domain Mutants
Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 15 genes
Gene families
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these 15 genes by gene family
Show members
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16 source identifiers mapped to 15 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000101384
182
JAG1
jagged canonical Notch ligand 1 [S...
ENSG00000101752
57534
MIB1
MIB E3 ubiquitin protein ligase 1 ...
ENSG00000107954
9148
NEURL1
neuralized E3 ubiquitin protein li...
ENSG00000128917
54567
DLL4
delta like canonical Notch ligand ...
ENSG00000137845
102
ADAM10
ADAM metallopeptidase domain 10 [S...
ENSG00000143947
6233
RPS27A
ribosomal protein S27a [Source:HGN...
ENSG00000148400
4851
NOTCH1
notch receptor 1 [Source:HGNC Symb...
ENSG00000150991
7316
UBC
ubiquitin C [Source:HGNC Symbol;Ac...
ENSG00000151694
6868
ADAM17
ADAM metallopeptidase domain 17 [S...
ENSG00000170315
7314
UBB
ubiquitin B [Source:HGNC Symbol;Ac...
ENSG00000184916
3714
JAG2
jagged canonical Notch ligand 2 [S...
ENSG00000197530
142678
MIB2
MIB E3 ubiquitin protein ligase 2 ...
ENSG00000198719
28514
DLL1
delta like canonical Notch ligand ...
ENSG00000214357
54492
NEURL1B
neuralized E3 ubiquitin protein li...
ENSG00000221983
7311
UBA52
ubiquitin A-52 residue ribosomal p...
ENSG00000275555
28514
DLL1
delta like canonical Notch ligand ...
Version history
2024.1.Hs: Updated to Reactome v89
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