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Human Gene Set: REACTOME_SIGNALING_BY_LEPTIN
Standard name
REACTOME_SIGNALING_BY_LEPTIN
Systematic name
M27195
Brief description
Signaling by Leptin
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-2586552
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-2586552
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 11 genes
Gene families
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Categorize
these 11 genes by gene family
Show members
(
show
11 source identifiers mapped to 11 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000096968
3717
JAK2
Janus kinase 2 [Source:HGNC Symbol;A...
ENSG00000116678
3953
LEPR
leptin receptor [Source:HGNC Symbol;...
ENSG00000126561
6776
STAT5A
signal transducer and activator of t...
ENSG00000168610
6774
STAT3
signal transducer and activator of t...
ENSG00000169047
3667
IRS1
insulin receptor substrate 1 [Source...
ENSG00000173757
6777
STAT5B
signal transducer and activator of t...
ENSG00000174697
3952
LEP
leptin [Source:HGNC Symbol;Acc:HGNC:...
ENSG00000178188
25970
SH2B1
SH2B adaptor protein 1 [Source:HGNC ...
ENSG00000179295
5781
PTPN11
protein tyrosine phosphatase non-rec...
ENSG00000184557
9021
SOCS3
suppressor of cytokine signaling 3 [...
ENSG00000185950
8660
IRS2
insulin receptor substrate 2 [Source...
Version history
2024.1.Hs: Updated to Reactome v89
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