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Human Gene Set: REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION
Standard name
REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION
Systematic name
M27208
Brief description
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-2892245
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-2892245
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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Please note that clustering takes a few seconds
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 10 genes
Gene families
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Categorize
these 10 genes by gene family
Show members
(
show
16 source identifiers mapped to 10 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000102804
8848
TSC22D1
TSC22 domain family member 1 [Sour...
ENSG00000107984
22943
DKK1
dickkopf WNT signaling pathway inh...
ENSG00000111704
79923
NANOG
Nanog homeobox [Source:HGNC Symbol...
ENSG00000133937
145258
GSC
goosecoid homeobox [Source:HGNC Sy...
ENSG00000141448
2627
GATA6
GATA binding protein 6 [Source:HGN...
ENSG00000152804
3087
HHEX
hematopoietically expressed homeob...
ENSG00000163508
8320
EOMES
eomesodermin [Source:HGNC Symbol;A...
ENSG00000165556
1045
CDX2
caudal type homeobox 2 [Source:HGN...
ENSG00000181449
6657
SOX2
SRY-box transcription factor 2 [So...
ENSG00000204531
5460
POU5F1
POU class 5 homeobox 1 [Source:HGN...
ENSG00000206454
5460
POU5F1
POU class 5 homeobox 1 [Source:HGN...
ENSG00000229094
5460
POU5F1
POU class 5 homeobox 1 [Source:HGN...
ENSG00000230336
5460
POU5F1
POU class 5 homeobox 1 [Source:HGN...
ENSG00000233911
5460
POU5F1
POU class 5 homeobox 1 [Source:HGN...
ENSG00000235068
5460
POU5F1
POU class 5 homeobox 1 [Source:HGN...
ENSG00000237582
5460
POU5F1
POU class 5 homeobox 1 [Source:HGN...
Version history
2024.1.Hs: Updated to Reactome v89
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