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Human Gene Set: REACTOME_NOTCH4_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS
Standard name
REACTOME_NOTCH4_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS
Systematic name
M27882
Brief description
NOTCH4 Activation and Transmission of Signal to the Nucleus
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-9013700
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-9013700
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 11 genes
Gene families
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these 11 genes by gene family
Show members
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show
14 source identifiers mapped to 11 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000080815
5663
PSEN1
presenilin 1 [Source:HGNC Symbol;Acc...
ENSG00000101384
182
JAG1
jagged canonical Notch ligand 1 [Sou...
ENSG00000117362
51107
APH1A
aph-1 homolog A, gamma-secretase sub...
ENSG00000128917
54567
DLL4
delta like canonical Notch ligand 4 ...
ENSG00000137845
102
ADAM10
ADAM metallopeptidase domain 10 [Sou...
ENSG00000138613
83464
APH1B
aph-1 homolog B, gamma-secretase sub...
ENSG00000143801
5664
PSEN2
presenilin 2 [Source:HGNC Symbol;Acc...
ENSG00000162736
23385
NCSTN
nicastrin [Source:HGNC Symbol;Acc:HG...
ENSG00000164924
7534
YWHAZ
tyrosine 3-monooxygenase/tryptophan ...
ENSG00000204301
4855
NOTCH4
notch receptor 4 [Source:HGNC Symbol...
ENSG00000205155
55851
PSENEN
presenilin enhancer, gamma-secretase...
ENSG00000223355
4855
NOTCH4
notch receptor 4 [Source:HGNC Symbol...
ENSG00000234876
4855
NOTCH4
notch receptor 4 [Source:HGNC Symbol...
ENSG00000238196
4855
NOTCH4
notch receptor 4 [Source:HGNC Symbol...
Version history
2024.1.Hs: Updated to Reactome v89
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