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Human Gene Set: REACTOME_FBXW7_MUTANTS_AND_NOTCH1_IN_CANCER
Standard name
REACTOME_FBXW7_MUTANTS_AND_NOTCH1_IN_CANCER
Systematic name
M27197
Brief description
FBXW7 Mutants and NOTCH1 in Cancer
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-2644605
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-2644605
Filtered by similarity
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1 similar pathway(s) from the external resource)
External ID
External Name
R-HSA-2644607
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 5 genes
Gene families
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Show members
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5 source identifiers mapped to 5 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000055130
8454
CUL1
cullin 1 [Source:HGNC Symbol;Acc:HGN...
ENSG00000100387
9978
RBX1
ring-box 1 [Source:HGNC Symbol;Acc:H...
ENSG00000109670
55294
FBXW7
F-box and WD repeat domain containin...
ENSG00000113558
6500
SKP1
S-phase kinase associated protein 1 ...
ENSG00000148400
4851
NOTCH1
notch receptor 1 [Source:HGNC Symbol...
Version history
2024.1.Hs: Updated to Reactome v89
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