Human Gene Set: REACTOME_DOUBLE_STRAND_BREAK_REPAIR
Standard name
REACTOME_DOUBLE_STRAND_BREAK_REPAIR
Systematic name
M15652
Brief description
Genes involved in Double-Strand Break Repair
Full description or abstract
Collection
ARCHIVED: Archived Founder gene sets that are referenced by current Hallmarks C2_CP: ARCHIVED Canonical Pathways C2_CP:REACTOME: ARCHIVED Reactome Pathways
Source publication
Exact source
R-HSA-73890
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-73890
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Reactome
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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format: grp | gmt | xml | json | TSV metadata
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(show 24 source identifiers mapped to 23 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
10111
10111
RAD50
RAD50 double strand break repair protein [S...
2547
2547
XRCC6
X-ray repair cross complementing 6 [Source:...
3014
3014
H2AX
H2A.X variant histone [Source:HGNC Symbol;A...
389901
389901
XRCC6P2
X-ray repair cross complementing 6 pseudoge...
3978
3978
LIG1
DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6...
3981
3981
LIG4
DNA ligase 4 [Source:HGNC Symbol;Acc:HGNC:6...
4361
4361
MRE11
MRE11 homolog, double strand break repair n...
4683
4683
NBN
nibrin [Source:HGNC Symbol;Acc:HGNC:7652]
472
472
ATM
ATM serine/threonine kinase [Source:HGNC Sy...
55775
55775
TDP1
tyrosyl-DNA phosphodiesterase 1 [Source:HGN...
5591
5591
PRKDC
protein kinase, DNA-activated, catalytic su...
5888
5888
RAD51
RAD51 recombinase [Source:HGNC Symbol;Acc:H...
5893
5893
RAD52
RAD52 homolog, DNA repair protein [Source:H...
6117
6117
RPA1
replication protein A1 [Source:HGNC Symbol;...
6118
6118
RPA2
replication protein A2 [Source:HGNC Symbol;...
6119
6119
RPA3
replication protein A3 [Source:HGNC Symbol;...
651610
672
672
BRCA1
BRCA1 DNA repair associated [Source:HGNC Sy...
675
675
BRCA2
BRCA2 DNA repair associated [Source:HGNC Sy...
7158
7158
TP53BP1
tumor protein p53 binding protein 1 [Source...
7518
7518
XRCC4
X-ray repair cross complementing 4 [Source:...
7520
7520
XRCC5
X-ray repair cross complementing 5 [Source:...
83990
83990
BRIP1
BRCA1 interacting helicase 1 [Source:HGNC S...
9656
9656
MDC1
mediator of DNA damage checkpoint 1 [Source...
Version history
7.1: Updated to use stable Reactome ID.
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