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Human Gene Set: REACTOME_ALK_MUTANTS_BIND_TKIS
Standard name
REACTOME_ALK_MUTANTS_BIND_TKIS
Systematic name
M42522
Brief description
ALK mutants bind TKIs
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-9700645
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-9700645
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 12 genes
Gene families
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Categorize
these 12 genes by gene family
Show members
(
show
12 source identifiers mapped to 12 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000108946
5573
PRKAR1A
protein kinase cAMP-dependent type ...
ENSG00000115414
2335
FN1
fibronectin 1 [Source:HGNC Symbol;A...
ENSG00000115760
57448
BIRC6
baculoviral IAP repeat containing 6...
ENSG00000115808
6801
STRN
striatin [Source:HGNC Symbol;Acc:HG...
ENSG00000119866
53335
BCL11A
BCL11 transcription factor A [Sourc...
ENSG00000127946
3092
HIP1
huntingtin interacting protein 1 [S...
ENSG00000138032
5495
PPM1B
protein phosphatase, Mg2+/Mn2+ depe...
ENSG00000141367
1213
CLTC
clathrin heavy chain [Source:HGNC S...
ENSG00000143924
27436
EML4
EMAP like 4 [Source:HGNC Symbol;Acc...
ENSG00000171094
238
ALK
ALK receptor tyrosine kinase [Sourc...
ENSG00000172071
9451
EIF2AK3
eukaryotic translation initiation f...
ENSG00000181163
4869
NPM1
nucleophosmin 1 [Source:HGNC Symbol...
Version history
2024.1.Hs: Updated to Reactome v89
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