Human Gene Set: PRC2_EZH2_UP.V1_DN


Standard name PRC2_EZH2_UP.V1_DN
Systematic name M2737
Brief description Genes down-regulated in TIG3 cells (fibroblasts) upon knockdown of EZH2 [GeneID=2146] gene.
Full description or abstract The identification of gene expression changes in human embryonic fibroblast cells depleted of EZH2.
Collection C6: Oncogenic Signature
Source publication Pubmed 16618801   Authors: Bracken AP,Dietrich N,Pasini D,Hansen KH,Helin K
Exact source ko vs control; bottom 200 genes
Related gene sets (show 7 additional gene sets from the source publication)

(show 4 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 192 genes
Gene families ? Categorize these 192 genes by gene family
Show members (show 200 source identifiers mapped to 192 genes)
Version history 6.2: Renamed from PRC2_EZH2_UP.V1_UP

See MSigDB license terms here. Please note that certain gene sets have special access terms.