Human Gene Set: P53_DN.V2_UP


Standard name P53_DN.V2_UP
Systematic name M2694
Brief description Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of TP53 [GeneID=7157] gene by RNAi.
Full description or abstract Expression profiling of cells knocked-down for p53 and control un-infected cells and cells infected with siRNA against LacZ.
Collection C6: Oncogenic Signature
Source publication Pubmed 15892871   Authors: Elkon R,Rashi-Elkeles S,Lerenthal Y,Linhart C,Tenne T,Amariglio N,Rechavi G,Shamir R,Shiloh Y
Exact source p53_siRNA vs controls; top 150 genes (diff. of means)
Related gene sets (show 5 additional gene sets from the source publication)

(show 79 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 148 genes
Gene families ? Categorize these 148 genes by gene family
Show members (show 150 source identifiers mapped to 148 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.