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Human Gene Set: NFKB_Q6_01
Standard name
NFKB_Q6_01
Systematic name
M2549
Brief description
Genes having at least one occurrence of the motif NNNNKGGRAANTCCCN in the regions spanning 4 kb centered on their transcription starting sites [-2kb, +2kb]. This matches the transcription factor binding site V$NFKB_Q6_01 (v7.4 TRANSFAC).
Full description or abstract
Collection
C3: Regulatory Target
TFT: Transcription Factor Targets
TFT:TFT_LEGACY: TFT_Legacy
Source publication
Exact source
Related gene sets
External links
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Xiaohui Xie (Broad Institute)
Source platform or
identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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Please note that clustering takes a few seconds
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 237 genes
Gene families
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Categorize
these 237 genes by gene family
Show members
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show
237 source identifiers mapped to 237 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ACTN1
87
ACTN1
actinin alpha 1 [Source:HG...
AF1Q
10962
MLLT11
MLLT11 transcription facto...
ALG6
29929
ALG6
ALG6 alpha-1,3-glucosyltra...
AMOTL1
154810
AMOTL1
angiomotin like 1 [Source:...
ANKHD1
54882
ANKHD1
ankyrin repeat and KH doma...
AP1S2
8905
AP1S2
adaptor related protein co...
APPL
26060
APPL1
adaptor protein, phosphoty...
ARHGAP8
23779
ARHGAP8
Rho GTPase activating prot...
ARHGEF2
9181
ARHGEF2
Rho/Rac guanine nucleotide...
ARL8
221079
ARL5B
ADP ribosylation factor li...
ASCL3
56676
ASCL3
achaete-scute family bHLH ...
ASH1L
55870
ASH1L
ASH1 like histone lysine m...
ATP1B1
481
ATP1B1
ATPase Na+/K+ transporting...
BAI2
576
ADGRB2
adhesion G protein-coupled...
BATF
10538
BATF
basic leucine zipper ATF-l...
BAZ2B
29994
BAZ2B
bromodomain adjacent to zi...
BCL3
602
BCL3
BCL3 transcription coactiv...
BCL6B
255877
BCL6B
BCL6B transcription repres...
BDNF
627
BDNF
brain derived neurotrophic...
BIRC3
330
BIRC3
baculoviral IAP repeat con...
BLR1
643
CXCR5
C-X-C motif chemokine rece...
BM88
51286
CEND1
cell cycle exit and neuron...
BMF
90427
BMF
Bcl2 modifying factor [Sou...
BMP2K
55589
BMP2K
BMP2 inducible kinase [Sou...
C13orf25
407975
MIR17HG
miR-17-92a-1 cluster host ...
C14orf43
91748
MIDEAS
mitotic deacetylase associ...
C1QL1
10882
C1QL1
complement C1q like 1 [Sou...
C1orf16
9887
SMG7
SMG7 nonsense mediated mRN...
C21orf29
54084
TSPEAR
thrombospondin type lamini...
C2orf11
130132
RFTN2
raftlin family member 2 [S...
CAPON
9722
NOS1AP
nitric oxide synthase 1 ad...
CCL5
6352
CCL5
C-C motif chemokine ligand...
CD69
969
CD69
CD69 molecule [Source:HGNC...
CDW92
23446
SLC44A1
solute carrier family 44 m...
CENTB5
116983
ACAP3
ArfGAP with coiled-coil, a...
CHD4
1108
CHD4
chromodomain helicase DNA ...
CHD6
84181
CHD6
chromodomain helicase DNA ...
CLCN1
1180
CLCN1
chloride voltage-gated cha...
CNTNAP1
8506
CNTNAP1
contactin associated prote...
COL27A1
85301
COL27A1
collagen type XXVII alpha ...
CREB1
1385
CREB1
cAMP responsive element bi...
CSF3
1440
CSF3
colony stimulating factor ...
CTAGE4
100128553
CTAGE4
CTAGE family member 4 [Sou...
CXorf21
80231
TASL
TLR adaptor interacting wi...
CYLD
1540
CYLD
CYLD lysine 63 deubiquitin...
DAP3
7818
DAP3
death associated protein 3...
DCAMKL1
9201
DCLK1
doublecortin like kinase 1...
DDR1
780
DDR1
discoidin domain receptor ...
DGKI
9162
DGKI
diacylglycerol kinase iota...
DKFZp761C169
65056
GPBP1
GC-rich promoter binding p...
DUSP22
56940
DUSP22
dual specificity phosphata...
DUSP6
1848
DUSP6
dual specificity phosphata...
EBF
1879
EBF1
EBF transcription factor 1...
EBI3
10148
EBI3
Epstein-Barr virus induced...
EDG5
9294
S1PR2
sphingosine-1-phosphate re...
EDN2
1907
EDN2
endothelin 2 [Source:HGNC ...
EGF
1950
EGF
epidermal growth factor [S...
EHF
26298
EHF
ETS homologous factor [Sou...
EIF5A
1984
EIF5A
eukaryotic translation ini...
ELMO1
9844
ELMO1
engulfment and cell motili...
ENO3
2027
ENO3
enolase 3 [Source:HGNC Sym...
EP300
2033
EP300
E1A binding protein p300 [...
ERN1
2081
ERN1
endoplasmic reticulum to n...
ETV1
2115
ETV1
ETS variant transcription ...
FBXL12
54850
FBXL12
F-box and leucine rich rep...
FGF1
2246
FGF1
fibroblast growth factor 1...
FGF17
8822
FGF17
fibroblast growth factor 1...
FLJ10385
55135
WRAP53
WD repeat containing antis...
FLJ10597
55182
RNF220
ring finger protein 220 [S...
FLJ14466
84876
ORAI1
ORAI calcium release-activ...
FLJ20309
54891
INO80D
INO80 complex subunit D [S...
FLJ20315
54894
RNF43
ring finger protein 43 [So...
FLJ22405
64419
MTMR14
myotubularin related prote...
FLJ23861
151050
KANSL1L
KAT8 regulatory NSL comple...
FLJ33207
339855
KY
kyphoscoliosis peptidase [...
FLJ39370
132720
FAM241A
family with sequence simil...
FLJ40869
348654
GEN1
GEN1 Holliday junction 5' ...
FTHL17
53940
FTHL17
ferritin heavy chain like ...
FUT7
2529
FUT7
fucosyltransferase 7 [Sour...
G3BP
10146
G3BP1
G3BP stress granule assemb...
GABRB1
2560
GABRB1
gamma-aminobutyric acid ty...
GADD45B
4616
GADD45B
growth arrest and DNA dama...
GATA4
2626
GATA4
GATA binding protein 4 [So...
GNB1
2782
GNB1
G protein subunit beta 1 [...
GNG4
2786
GNG4
G protein subunit gamma 4 ...
GPHN
10243
GPHN
gephyrin [Source:HGNC Symb...
GPR2
2826
CCR10
C-C motif chemokine recept...
GREM1
26585
GREM1
gremlin 1, DAN family BMP ...
GRIN2D
2906
GRIN2D
glutamate ionotropic recep...
GRK5
2869
GRK5
G protein-coupled receptor...
HBXAP
51773
RSF1
remodeling and spacing fac...
HIVEP1
3096
HIVEP1
HIVEP zinc finger 1 [Sourc...
HSD11B2
3291
HSD11B2
hydroxysteroid 11-beta deh...
HSD3B7
80270
HSD3B7
hydroxy-delta-5-steroid de...
HSPC129
51496
CTDSPL2
CTD small phosphatase like...
HTR3B
9177
HTR3B
5-hydroxytryptamine recept...
ICAM1
3383
ICAM1
intercellular adhesion mol...
IER5
51278
IER5
immediate early response 5...
IFNB1
3456
IFNB1
interferon beta 1 [Source:...
IGSF4
23705
CADM1
cell adhesion molecule 1 [...
IL12A
3592
IL12A
interleukin 12A [Source:HG...
IL13
3596
IL13
interleukin 13 [Source:HGN...
IL1RN
3557
IL1RN
interleukin 1 receptor ant...
IL23A
51561
IL23A
interleukin 23 subunit alp...
IL27
246778
IL27
interleukin 27 [Source:HGN...
IL27RA
9466
IL27RA
interleukin 27 receptor su...
IL28A
282616
IFNL2
interferon lambda 2 [Sourc...
IL28B
282617
IFNL3
interferon lambda 3 [Sourc...
IL2RA
3559
IL2RA
interleukin 2 receptor sub...
IL4I1
259307
IL4I1
interleukin 4 induced 1 [S...
IL6ST
3572
IL6ST
interleukin 6 cytokine fam...
IL7
3574
IL7
interleukin 7 [Source:HGNC...
ILK
3611
ILK
integrin linked kinase [So...
JAK3
3718
JAK3
Janus kinase 3 [Source:HGN...
KIAA0409
23378
RRP8
ribosomal RNA processing 8...
KIAA1536
57658
CALCOCO1
calcium binding and coiled...
KLK9
284366
KLK9
kallikrein related peptida...
KRT23
25984
KRT23
keratin 23 [Source:HGNC Sy...
KRTAP13-1
140258
KRTAP13-1
keratin associated protein...
LNK
10019
SH2B3
SH2B adaptor protein 3 [So...
LOC168850
168850
ZNF800
zinc finger protein 800 [S...
LOC81558
81558
FAM117A
family with sequence simil...
LOC92162
92162
TMEM88
transmembrane protein 88 [...
LTA
4049
LTA
lymphotoxin alpha [Source:...
LTB
4050
LTB
lymphotoxin beta [Source:H...
MADCAM1
8174
MADCAM1
mucosal vascular addressin...
MAG
4099
MAG
myelin associated glycopro...
MAML2
84441
MAML2
mastermind like transcript...
MAP3K11
4296
MAP3K11
mitogen-activated protein ...
MAP4K2
5871
MAP4K2
mitogen-activated protein ...
MASK-BP3
404734
ANKHD1-EIF4EBP3
ANKHD1-EIF4EBP3 readthroug...
MGC31967
203260
CCDC107
coiled-coil domain contain...
MGC46719
128077
LIX1L
limb and CNS expressed 1 l...
MITF
4286
MITF
melanocyte inducing transc...
MMP9
4318
MMP9
matrix metallopeptidase 9 ...
MOBKL2C
148932
MOB3C
MOB kinase activator 3C [S...
MR-1
25953
PNKD
PNKD metallo-beta-lactamas...
MRPS6
64968
MRPS6
mitochondrial ribosomal pr...
MSC
9242
MSC
musculin [Source:HGNC Symb...
MSX1
4487
MSX1
msh homeobox 1 [Source:HGN...
NDRG2
57447
NDRG2
NDRG family member 2 [Sour...
NEK8
284086
NEK8
NIMA related kinase 8 [Sou...
NFAT5
10725
NFAT5
nuclear factor of activate...
NFKB2
4791
NFKB2
nuclear factor kappa B sub...
NFKBIA
4792
NFKBIA
NFKB inhibitor alpha [Sour...
NFKBIB
4793
NFKBIB
NFKB inhibitor beta [Sourc...
NLK
51701
NLK
nemo like kinase [Source:H...
NR2F2
7026
NR2F2
nuclear receptor subfamily...
NR3C1
2908
NR3C1
nuclear receptor subfamily...
NTN1
9423
NTN1
netrin 1 [Source:HGNC Symb...
NXF
266743
NPAS4
neuronal PAS domain protei...
OA48-18
51747
LUC7L3
LUC7 like 3 pre-mRNA splic...
PAPPA
5069
PAPPA
pappalysin 1 [Source:HGNC ...
PCBP4
57060
PCBP4
poly(rC) binding protein 4...
PCSK2
5126
PCSK2
proprotein convertase subt...
PFN1
5216
PFN1
profilin 1 [Source:HGNC Sy...
PHOX2B
8929
PHOX2B
paired like homeobox 2B [S...
POU2F3
25833
POU2F3
POU class 2 homeobox 3 [So...
PP1665
81544
GDPD5
glycerophosphodiester phos...
PPP1R13B
23368
PPP1R13B
protein phosphatase 1 regu...
PRDM12
59335
PRDM12
PR/SET domain 12 [Source:H...
PRKCD
5580
PRKCD
protein kinase C delta [So...
PTD015
28971
AAMDC
adipogenesis associated Mt...
PTGES
9536
PTGES
prostaglandin E synthase [...
PTHLH
5744
PTHLH
parathyroid hormone like h...
PTMS
5763
PTMS
parathymosin [Source:HGNC ...
PTPRJ
5795
PTPRJ
protein tyrosine phosphata...
RALGDS
5900
RALGDS
ral guanine nucleotide dis...
RAP2C
57826
RAP2C
RAP2C, member of RAS oncog...
RASGRP4
115727
RASGRP4
RAS guanyl releasing prote...
RASSF2
9770
RASSF2
Ras association domain fam...
RBMS1
5937
RBMS1
RNA binding motif single s...
RBPSUH
3516
RBPJ
recombination signal bindi...
RELB
5971
RELB
RELB proto-oncogene, NF-kB...
REV3L
5980
REV3L
REV3 like, DNA directed po...
RFX5
5993
RFX5
regulatory factor X5 [Sour...
RHOG
391
RHOG
ras homolog family member ...
RIN2
54453
RIN2
Ras and Rab interactor 2 [...
RND1
27289
RND1
Rho family GTPase 1 [Sourc...
SEC61A1
29927
SEC61A1
SEC61 translocon subunit a...
SEMA3B
7869
SEMA3B
semaphorin 3B [Source:HGNC...
SHOX2
6474
SHOX2
SHOX homeobox 2 [Source:HG...
SIN3A
25942
SIN3A
SIN3 transcription regulat...
SIRT2
22933
SIRT2
sirtuin 2 [Source:HGNC Sym...
SLAMF8
56833
SLAMF8
SLAM family member 8 [Sour...
SLC6A12
6539
SLC6A12
solute carrier family 6 me...
SLICK
343450
KCNT2
potassium sodium-activated...
SMC6L1
79677
SMC6
structural maintenance of ...
SMOC1
64093
SMOC1
SPARC related modular calc...
SMPD3
55512
SMPD3
sphingomyelin phosphodiest...
SNAP25
6616
SNAP25
synaptosome associated pro...
SOCS2
8835
SOCS2
suppressor of cytokine sig...
SOX5
6660
SOX5
SRY-box transcription fact...
SP6
80320
SP6
Sp6 transcription factor [...
SPEC1
56882
CDC42SE1
CDC42 small effector 1 [So...
STAT6
6778
STAT6
signal transducer and acti...
STN2
85439
STON2
stonin 2 [Source:HGNC Symb...
TA-NFKBH
84807
NFKBID
NFKB inhibitor delta [Sour...
TBX20
57057
TBX20
T-box transcription factor...
TCEA2
6919
TCEA2
transcription elongation f...
TCF1
6927
HNF1A
HNF1 homeobox A [Source:HG...
TFE3
7030
TFE3
transcription factor bindi...
TGIF
7050
TGIF1
TGFB induced factor homeob...
TJP4
93643
TJAP1
tight junction associated ...
TNFRSF1B
7133
TNFRSF1B
TNF receptor superfamily m...
TNFRSF5
958
CD40
CD40 molecule [Source:HGNC...
TNFRSF9
3604
TNFRSF9
TNF receptor superfamily m...
TNFSF15
9966
TNFSF15
TNF superfamily member 15 ...
TNFSF18
8995
TNFSF18
TNF superfamily member 18 ...
TNFSF7
970
CD70
CD70 molecule [Source:HGNC...
TNIP1
10318
TNIP1
TNFAIP3 interacting protei...
TNIP3
79931
TNIP3
TNFAIP3 interacting protei...
TOP1
7150
TOP1
DNA topoisomerase I [Sourc...
TP53
7157
TP53
tumor protein p53 [Source:...
TP73L
8626
TP63
tumor protein p63 [Source:...
TRA1
7184
HSP90B1
heat shock protein 90 beta...
TRAF4
9618
TRAF4
TNF receptor associated fa...
TRIB2
28951
TRIB2
tribbles pseudokinase 2 [S...
TRIM47
91107
TRIM47
tripartite motif containin...
TSLP
85480
TSLP
thymic stromal lymphopoiet...
UACA
55075
UACA
uveal autoantigen with coi...
UBD
10537
UBD
ubiquitin D [Source:HGNC S...
UBE2D3
7323
UBE2D3
ubiquitin conjugating enzy...
UBE2H
7328
UBE2H
ubiquitin conjugating enzy...
UBE2I
7329
UBE2I
ubiquitin conjugating enzy...
UNC84B
25777
SUN2
Sad1 and UNC84 domain cont...
UPF2
26019
UPF2
UPF2 regulator of nonsense...
USP52
9924
PAN2
poly(A) specific ribonucle...
VCAM1
7412
VCAM1
vascular cell adhesion mol...
WNT10A
80326
WNT10A
Wnt family member 10A [Sou...
XPO6
23214
XPO6
exportin 6 [Source:HGNC Sy...
YAP
55249
YY1AP1
YY1 associated protein 1 [...
ZBTB11
27107
ZBTB11
zinc finger and BTB domain...
ZBTB9
221504
ZBTB9
zinc finger and BTB domain...
ZIC4
84107
ZIC4
Zic family member 4 [Sourc...
ZNF161
7716
VEZF1
vascular endothelial zinc ...
ZNRF1
84937
ZNRF1
zinc and ring finger 1 [So...
Version history
7.1: Moved to TFT_Legacy sub-collection.
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.